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APH(3')-IIIa

National Institutes of Health

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Broader (1)

Kanamycin Kinase

Papers overview

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2020
2020
Role of Asp190 in the Phosphorylation of the Antibiotic Kanamycin Catalyzed by the Aminoglycoside Phosphotransferase enzyme: A Combined QM:QM and MD Study.
The aminoglycoside phosphotransferase (APH(3')-IIIa) kinases form a clinically central group of antibiotic-resistant enzymes… 
2017
2017
Characterization of high level ampicillin‐ and aminoglycoside‐resistant enterococci isolated from non‐hospital sources
Purpose. High level ampicillin‐ and aminoglycoside‐resistant enterococci are being increasingly reported from non‐hospital… 
2017
2017
شناسایی ژن aph(3')-IIIa مقاوم به استرپتومایسین در ایزوله های جداشده از بیماران شهر تهران با روش مولکولی PCR
2016
2016
Detection of Aminoglycoside and Macrolide Resistance Mechanisms in Methicillin-Resistant Staphylococcus Aureus.
Methicillin-resistant Staphylococcus aureus can become resistant to many different classes of antibiotics. Objective: To… 
2013
2013
Directed Evolution of Aminoglycoside Phosphotransferase (3′) Type IIIa Variants That Inactivate Amikacin but Impose Significant Fitness Costs
The rules that govern adaptive protein evolution remain incompletely understood. Aminoglycoside aminotransferase (3′) type IIIa… 
2013
2013
Rv3168 phosphotransferase activity mediates kanamycin resistance in Mycobacterium tuberculosis.
Tuberculosis is a worldwide epidemic disease caused by Mycobacterium tuberculosis, with an estimated one-third of the human… 
2008
2008
Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
The modification of proteins by reducing sugars through the process of non-enzymatic glycation is one of the principal mechanisms… 
2008
2008
Distribution of Genes Encoding Aminoglycoside Modifying Enzymes and Type Staphylococcal Chromosomal Cassette mec in Methicillin-resistant Staphylococcus aureus from Non-tertiary Hospitals
Background : Many genes encoding aminoglycoside modifying enzymes (AMEs) on transposon or plasmid were transferred from one… 
2000
2000
The Role of a Second Magnesium Ion in APH(3')-IIIa
Due to the overprescription and misuse of antibiotics, an environment has been created which has allowed a number of resistant… 
1999
1999
Characterization of aminoglycoside phosphotransferase APH(3')-IIIa, an enterococcal enzyme conferring resistance to aminoglycoside antibiotics
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