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National Institutes of Health
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APC0576 decreases production of pro-inflammatory chemokine and extracellular matrix by human Tenon's capsule fibroblasts
Corpus ID: 88371042
APC0576 decreases production of pro-inflammatory chemokine and extracellular matrix by human Tenon's capsule fibroblasts.
Experimental eye research
Corpus ID: 36257165
PURPOSE To control intraocular pressure in patients treated by trabeculectomy, progressive inflammation, fibroblast proliferation…
APC0576: A novel small molecule, immunosuppressive agent effective in primate models
Corpus ID: 24537506
Background. APC0576, 5-(((S)-2,2-dimethylcyclopropanecarbonyl)amino)-2-(4-(((S)-2,2-dimethylcyclopropanecarbonyl)amino)phenoxy…
APC0576, a novel inhibitor of NF-kappaB-dependent gene activation, prevents pro-inflammatory cytokine-induced chemokine production in human endothelial cells.
Biochemical and biophysical research…
Corpus ID: 42151132
Endothelial cells participate in the inflammatory and immune reactions. Endothelial cell activation is a recurrent phenomenon…
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