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Breast cancer development and progression are influenced by insulin-like growth factor receptor 1 (IGF1R) and insulin receptor… Expand Adoptive immunotherapy using chimeric antigen receptors-modified T cells (CAR-T) is a promising approach for cancer treatment… Expand The gradual emerging of resistance to imatinib urgently calls for the development of new therapy for chronic myeloid leukemia… Expand The presence and abundance of proteins in the plasma membrane (PM) is regulated by exocytosis and endocytosis. Exocytosis is… Expand The function of cell surface proteins likely involves the formation and dissociation of oligomeric complexes. However, the… Expand Post-translational modifications control the physiological activity of the signal transducer and activator of transcription STAT1… Expand Trafficking of proteins between the cytoplasm and nucleus occurs exclusively across the nuclear pore complex of eucaryotic cells… Expand Gene therapy using constitutively active viral promoters to drive expression of bone morphogenetic proteins (BMPs) has been… Expand Ovarian cancer represents a malignancy suitable for cell and gene therapy approaches owing to its containment within the… Expand Replication-competent adenoviral vectors are potentially far more efficient than replication-defective vectors. However, for… Expand