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AO 128

Known as: AO-128, epi-Inositol, 2,3-dideoxy-2-((2-hydroxy-1-(hydroxymethyl)ethyl)amino)-4-C-(hydroxymethyl)- 
National Institutes of Health

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2 relations

Broader (2)

Cyclohexanolsvoglibose

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Concomitant administration of the α-glucosidase inhibitor voglibose (AO-128) does not alter the pharmacokinetics of glibenclamide
Objective: Voglibose is a new and potent inhibitor of α-glucosidases used for treatment of diabetes mellitus. It increases gastro… 
1997
1997
Slight but significant improvement of insulin resistance of Wistar fatty rats by treatment with a disaccharidase inhibitor, AO-128.
To know whether the insulin resistance is improved by delaying carbohydrate absorption from the small intestine, we studied the… 
1995
1995
An alpha-glucosidase inhibitor, AO-128, retards carbohydrate absorption in rats and humans.
The present study was designed to determine the possible significance of a therapeutic dose (0.2 mg) of AO-128 on carbohydrate… 
1995
1995
AO-128, alpha-glucosidase inhibitor: antiobesity and antidiabetic actions in genetically obese-diabetic rats, Wistar fatty.
Antiobesity and antidiabetic actions of the alpha-glucosidase inhibitor AO-128 were examined using genetically obese-diabetic… 
1995
1995
Voglibose (AO-128) : A hypoglycemic agent.
1993
1993
Effect of an α-Glucosidase Inhibitor on Intestinal Fermentation and Faecal Lipids in Diabetic Patients
Eight non-insulin-dependent diabetes mellitus patients, in whom oral hypoglycaemic agents were not effective, were treated with… 
Highly Cited
1992
Highly Cited
1992
Differences in glucagon-like peptide-1 and GIP responses following sucrose ingestion.
1992
1992
Antiobesity and antidiabetic actions of a new potent disaccharidase inhibitor in genetically obese-diabetic mice, KKA(y).
AO-128 is a potent and structurally novel inhibitor of the intestinal disaccharidases, such as maltase and sucrase. Genetically… 
1990
1990
Inhibitory effect of a new alpha-glucosidase inhibitor on fatty liver in Zucker fatty rats.
The livers of Zucker fatty (fa/fa) and lean (Fa/-) rats treated with standard rat chow diet containing 0, 10 or 50 ppm alpha… 
1989
1989
Metabolic improvements associated with a reduction of abdominal visceral fat caused by a new α-glucosidase inhibitor, AO-128, in Zucker fatty rats
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