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ANGPTL3 gene

Known as: ANGIOPOIETIN 5, ANGIOPOIETIN-LIKE 3, ANGPTL3 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
CHARACTERIZATION OF ANGPTL3 DEFICIENCY AND MOLECULAR MECHANISMS OF ANGPTL3 DEFICIENCY-INDUCED HYPOLIPIDEMIA
Introduction and aims: ANGPTL3 is a hepatokine and a regulator of lipid metabolism primarily via its inhibitory effect on… 
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Highly Cited
2017
Highly Cited
2017
ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance[S]
Angiopoietin-like (ANGPTL)3 and ANGPTL8 are secreted proteins and inhibitors of LPL-mediated plasma triglyceride (TG) clearance… 
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Highly Cited
2017
Highly Cited
2017
ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase
Objective Several members of the angiopoietin-like (ANGPTL) family of proteins, including ANGPTL3 and ANGPTL8, regulate… 
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2017
2017
Clinical and biochemical characteristics of individuals with low cholesterol syndromes: A comparison between familial hypobetalipoproteinemia and familial combined hypolipidemia.
BACKGROUND The most frequent monogenic causes of low plasma cholesterol are familial hypobetalipoproteinemia (FHBL1) because of… 
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Highly Cited
2017
Highly Cited
2017
Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides
BACKGROUND Epidemiologic and genomewide association studies have linked loss‐of‐function variants in ANGPTL3, encoding… 
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Review
2015
Review
2015
The role of ANGPTL3 in controlling lipoprotein metabolism
Angiopoietin-like protein 3 (ANGPTL3) is a secretory protein regulating plasma lipid levels via affecting lipoprotein lipase- and… 
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2015
2015
ANGPTL3 is a novel biomarker as it activates ERK/MAPK pathway in oral cancer
Angiopoietin‐like 3 (ANGPTL3), which is involved in new blood vessel growth and stimulation of mitogen‐activated protein kinase… 
2013
2013
Peroxisome proliferator-activated receptor-β/δ regulates angiogenic cell behaviors and oxygen-induced retinopathy.
PURPOSE To develop new therapies against ocular neovascularization (NV), we tested the effect of peroxisome proliferator… 
2012
2012
Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines.
Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths throughout the world. Angiopoietin… 
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Highly Cited
2012
Highly Cited
2012
Atypical angiopoietin-like protein that regulates ANGPTL3
  • F. Quagliarini, Yan Wang, +7 authors H. Hobbs
  • Proceedings of the National Academy of Sciences
  • 2012
  • Corpus ID: 22750145
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a… 
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