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AMRI-59

National Institutes of Health

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AcetophenonesPiperidines

Papers overview

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2017
2017
AMRI-59 functions as a radiosensitizer via peroxiredoxin I-targeted ROS accumulation and apoptotic cell death induction
Previously, we identified AMRI-59 as a specific pharmaceutical inhibitor of peroxiredoxin (PRX) I enzyme activity. In this study… 
2017
2017
Abstract 5853: Peroxiredoxin I-targeted AMRI-59 has a role of radiosensitizer by promoting induction of ROS/γH2AX/caspase pathway and suppression of ERK
We have identified AMRI-59, one of small molecule, is specific pharmaceutical inhibitor of peroxiredoxin (PRX) I enzyme activity… 
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