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AMPA glutamate receptor complex

Known as: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, AMPA-selective glutamate receptor complex, AMPA glutamate receptor complex location 
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding… 
National Institutes of Health

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AMPA receptor location

Papers overview

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2019
2019
Electrophysiological characterization of a novel AMPA receptor potentiator, TAK-137, in rat hippocampal neurons
2015
2015
Understanding responder neurobiology in schizophrenia using a quantitative systems pharmacology model: Application to iloperidone
The concept of targeted therapies remains a holy grail for the pharmaceutical drug industry for identifying responder populations… 
2013
2013
Avaliação da exposição aguda e sub-letal ao glifosato (N-fosfometil-glicina) e ao AMPA (ácido amino-metil-fosfônico) em brânquias e fígado de Poecilia reticulata com o emprego de biomarcadores…
A presente pesquisa teve como objetivo investigar a toxicidade aguda do Glifosato (Nfosfometil-glicina), principio ativo dos… 
2008
2008
The quaternary structure of a calcium-permeable AMPA receptor: conservation of shape and symmetry across functionally distinct subunit assemblies.
2000
2000
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Intracellular Ca(2+) ([Ca(2+)](i)) was fluorometrically measured with fura-2 in lumbar motoneurons of acutely isolated spinal… 
1999
1999
Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat
1998
1998
Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
We have previously shown that (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA, 2] is a weak agonist at… 
1997
1997
AMPA receptor agonists: resolution, configurational assignment, and pharmacology of (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4-yl]-propionic acid (2-Py-AMPA).
We have previously shown that whereas (RS)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid (APPA) shows the… 
1997
1997
Bioisosterically modified dipeptide excitatory amino acid receptor antagonists containing 3-oxygenated isothiazole ring systems.
Highly Cited
1993
Highly Cited
1993
Intracellular Mechanisms Underlying the Suppression of AMPA Responses by trans-ACPD in Cultured Chick Purkinje Neurons
Intracellular mechanisms underlying the functional suppression of ionotropic glutamate receptors by activation of metabotropic… 
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