AMINOTHIAZOLE

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
05101519452017

Papers overview

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2016
2016
BACKGROUND Leukotrienes are pivotal lipid mediators in various immune and inflammatory reactions. Herein, 5-LO is a validated… (More)
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2013
2013
Recently, we described the aminothiazole lead (4-biphenyl-4-ylthiazol-2-yl)-(6-methylpyridin-2-yl)-amine (1), which exhibits many… (More)
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2011
2011
2-Aminothiazoles are a new class of small molecules with antiprion activity in prion-infected neuroblastoma cell lines (J. Virol… (More)
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2011
2011
We herein report the discovery of a new γ-secretase modulator class with an aminothiazole core starting from a HTS hit (3… (More)
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2008
2008
Oceans are among the richest natural sources of many bioactive compounds. Several of these compounds have shown pharmacological… (More)
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2008
2008
Aurora family kinases regulate important events during mitosis including centrosome maturation and separation, mitotic spindle… (More)
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2005
2005
Aminothiazole-based inhibitors designed for HCV polymerase display low micromolar potencies in biochemical assays. These… (More)
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2004
2004
A series of aminothiazole-derived morphinans, benzomorphans, and morphine were synthesized. Although their affinities were… (More)
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1996
1996
For the development of novel antioxidants having therapeutic utility, a new series of condensed 4- and 5-aminothiazole… (More)
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1987
1987
The enantiomers of the aminothiazole analogues of the known dopaminergic agonists apomorphine (1) and 2-aminohydroxytetralin (2… (More)
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