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AMG 330

Known as: Bispecific T-cell Engager Antibody AMG 330, AMG330, Anti-CD33/CD3 BiTE Antibody AMG 330 
A proprietary recombinant bispecific T-cell engager (BiTE) antibody composed of two single-chain variable fragments (scFv), one directed against the… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Antibodies, Bispecific
NCIt Antineoplastic Agent Terminologyantigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
PD-1/PD-L1 Blocking Enhances CD33/CD3-Bispecific BiTE® Antibody (AMG 330) Mediated Lysis of Primary AML Cells
Antibody-based immunotherapy represents a promising strategy to target and eliminate chemoresistant leukemic cells in acute… 
2013
2013
Evaluation Of CD33 Expression and Functional Analysis Of The CD33/CD3 Bispecific BiTE® Antibody AMG 330 In Primary AML Samples
Antibody-based immunotherapy represents a promising strategy to specifically target and eliminate chemoresistant leukemic cells… 
2009
2009
Verordnung (EG) Nr. 1394/2007 über Arzneimittel für neuartige Therapien
ZusammenfassungDie Verordnung (EG) Nr. 1394/2007 hat für die Arzneimittel für neuartige Therapien (Gentherapeutika, somatische… 
2009
2009
Bedeutung von Multicenterstudiengruppen für die klinische Forschung in der Hämatologie und Onkologie
ZusammenfassungAuf dem Gebiet der Hämatologie wurde in den vergangenen 25 Jahren eine besonders effektive Studieninfrastruktur… 
2001
2001
Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells.
Mast cells permeabilized by streptolysin O undergo exocytosis when stimulated with Ca(2+) and guanosine 5'-[gamma-thio… 
1998
1998
Atypical protein kinase C isozyme zeta mediates carbachol-stimulated insulin secretion in RINm5F cells.
Carbachol-stimulated insulin release in the RINm5F cell is associated with elevation of the cytosolic Ca2+ concentration ([Ca2+]i… 
1993
1993
Enhancement of thyrotropin-stimulated iodide organification in porcine thyroid cells after protein kinase-C inhibition.
We and others have previously shown that 12-O-tetracanoylphorbol-13-acetate (TPA), a protein kinase-C (PKC) activator, inhibits… 
1990
1990
Ether lipid (AMG) exhibits both synergistic and inhibitory interactions with the ionophore A23187 in mast cell histamine release.
Highly Cited
1989
Highly Cited
1989
1-O-hexadecyl-2-Q-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils.
1987
1987
A metabolite of an antineoplastic ether phospholipid may inhibit transmembrane signalling via protein kinase C
In our search for the mechanisms by which the drug 1-O-alkyl-2-O-methylglycero-3-phosphocholine (AMG-PC) inhibits tumor growth… 
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