AMG 073

Known as: AMG073, KRN 1493, 1493, KRN 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2011
02420022011

Papers overview

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2007
2007
Calcimimetics are a class of compounds that positively modulate the calcium-sensing receptor (CaR) by allosterically increasing… (More)
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Review
2004
Review
2004
Diseases, together with a short overview article. These manuscripts are readily available for free by visiting the following web… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND A need exists for a therapy that lowers parathyroid hormone (PTH) without increasing calcium x phosphorus in patients… (More)
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Highly Cited
2003
Highly Cited
2003
Current treatment of secondary hyperparathyroidism in chronic kidney failure with calcium and active vitamin D is potentially… (More)
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Review
2003
Review
2003
  • Drugs in R&D
  • 2003
Cinacalcet [AMG 073, KRN 1493, NPS 1493] is an orally active, second-generation calcimimetic compound licensed by NPS… (More)
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2003
2003
This study examined whether the calcium-sensing receptor (CaR) is expressed in normal adult human osteoblastic and osteoclastic… (More)
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Review
2003
Review
2003
Cinacalcet HCl (AMG 073) is an investigational oral calcimimetic drug currently being evaluated for the treatment of primary and… (More)
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Highly Cited
2002
Highly Cited
2002
Treatment with vitamin D sterols can lower plasma parathyroid hormone (PTH) in many patients with secondary hyperparathyroidism… (More)
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Review
2002
Review
2002
Recognition of the role of the extracellular calcium sensing receptor (CaR) in mineral metabolism has greatly improved our… (More)
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Review
2002
Review
2002
Calcimimetic agents are small organic molecules that act as allosteric activators of the calcium-sensing receptor. In parathyroid… (More)
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