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cinacalcet hydrochloride

Known as: Hydrochloride, Cinacalcet, 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride, Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride 
The orally bioavailable hydrochloride salt of the calcimimetic cinacalcet. Cinacalcet increases the sensitivity of calcium-sensing receptors on chief… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Background— Patients with kidney disease have disordered bone and mineral metabolism, including elevated serum concentrations of… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND OBJECTIVES Fibroblast growth factor-23 (FGF23) levels are elevated in ESRD and have been associated with adverse… Expand
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Review
2009
Review
2009
Cinacalcet hydrochloride (cinacalcet) is a calcimimetic approved for the treatment of secondary hyperparathyroidism in patients… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Cinacalcet hydrochloride (KRN1493) acts on the parathyroid calcium receptors to suppress parathyroid hormone (PTH… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND AND OBJECTIVES Patients with chronic kidney disease (CKD) receiving dialysis often develop secondary… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Management of inoperable parathyroid carcinoma presents a challenge because until recently, effective medical therapy… Expand
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Review
2007
Review
2007
G-protein-coupled receptors (GPCRs) are, and will probably remain, the most tractable class of targets for the development of… Expand
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Highly Cited
2005
Highly Cited
2005
Calcimimetics increase the sensitivity of parathyroid calcium-sensing receptors to extracellular calcium, thereby reducing PTH… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Secondary hyperparathyroidism develops early in patients with chronic kidney disease (CKD). Clinical guidelines from… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Treatment of secondary hyperparathyroidism with vitamin D and calcium in patients receiving dialysis is often… Expand
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