cinacalcet hydrochloride

Known as: Hydrochloride, Cinacalcet, 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride, Alpha-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-1-naphthalenemethanamine, (alphaR)-hydrochloride 
The orally bioavailable hydrochloride salt of the calcimimetic cinacalcet. Cinacalcet increases the sensitivity of calcium-sensing receptors on chief… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Patients with kidney disease have disordered bone and mineral metabolism, including elevated serum concentrations of… (More)
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Highly Cited
2010
Highly Cited
2010
Secondary hyperparathyroidism (SHPT) affects a significant number of hemodialysis patients, and metabolic disturbances associated… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND OBJECTIVES Fibroblast growth factor-23 (FGF23) levels are elevated in ESRD and have been associated with adverse… (More)
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Review
2009
Review
2009
Cinacalcet hydrochloride (cinacalcet) is a calcimimetic approved for the treatment of secondary hyperparathyroidism in patients… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Management of inoperable parathyroid carcinoma presents a challenge because until recently, effective medical therapy… (More)
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2006
2006
An underrecognized side effect of long-term lithium carbonate therapy is hyperparathyroidism with associated hypercalcemia and… (More)
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Highly Cited
2005
Highly Cited
2005
Calcimimetics increase the sensitivity of parathyroid calcium-sensing receptors to extracellular calcium, thereby reducing PTH… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Secondary hyperparathyroidism develops early in patients with chronic kidney disease (CKD). Clinical guidelines from… (More)
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2005
2005
Currently, >300,000 patients with end-stage renal disease require dialysis. Secondary hyperparathyroidism is a serious… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Treatment of secondary hyperparathyroidism with vitamin D and calcium in patients receiving dialysis is often… (More)
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