Skip to search formSkip to main contentSkip to account menu

AMD3100

Known as: AMD 3100, AMD-3100, SDZ SID 791 
A bicyclam with hematopoietic stem cell-mobilizing properties. AMD3100 blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular… 
National Institutes of Health

Related topics

Related topics

2 relations
JM 3100

Broader (1)

Plerixafor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Sulfated polysaccharide isolated from the sea cucumber Stichopus japonicas promotes the SDF-1α/CXCR4 axis-induced NSC migration via the PI3K/Akt/FOXO3a, ERK/MAPK, and NF-κB signaling pathways
Highly Cited
2013
Highly Cited
2013
Inhibition of CXCL12 Signaling Attenuates the Postischemic Immune Response and Improves Functional Recovery after Stroke
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing… 
Highly Cited
2011
Highly Cited
2011
Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases.
2011
2011
Effects of SDF-1-CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells.
2010
2010
Differences in donor CXCR4 expression levels are correlated with functional capacity and therapeutic outcome of angiogenic treatment with endothelial colony forming cells.
2010
2010
Plerixafor (Mozobil) alone to mobilize hematopoietic stem cells from multiple myeloma patients for autologous transplantation.
Highly Cited
2008
Highly Cited
2008
Synergy between Coproduced CC and CXC Chemokines in Monocyte Chemotaxis through Receptor-Mediated Events
CC and CXC chemokines coinduced in fibroblasts and leukocytes by cytokines and microbial agents determine the number of… 
Highly Cited
2006
Highly Cited
2006
Stromal cell‐derived factor‐1α modulation of the excitability of rat substantia nigra dopaminergic neurones: presynaptic mechanisms
In rat substantia nigra (SN), Chemokine (CXC motif) receptor 4 (CXCR4) for the chemokine stromal cell‐derived factor (SDF)‐1α is… 
2005
2005
Stromal cell‐derived factor‐1α directly modulates voltage‐dependent currents of the action potential in mammalian neuronal cells
Stromal cell‐derived factor‐1α (SDF‐1α) is a chemokine whose receptor, CXCR4, is distributed in specific brain areas including… 
Review
2003
Review
2003
The bicyclam AMD3100 story
The discovery and development of the bicyclam AMD3100 — a chemokine receptor antagonist — has highlighted the therapeutic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)