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AMD3100

Known as: AMD 3100, AMD-3100, SDZ SID 791 
A bicyclam with hematopoietic stem cell-mobilizing properties. AMD3100 blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular… 
National Institutes of Health

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Papers overview

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2018
2018
CXCR4 antagonist AMD3100 protects TGFβ1 induced viability and migration in rat cardiac fibroblasts
Proliferation and migration of Cardiac Fibroblasts (CFBs) are important in early stage of myocardial fibrosis. The purpose of the… 
2012
2012
Maximizing the efficacy of angiogenesis inhibitors.
TO THE EDITOR: The article “Phase II Study of Aflibercept in Recurrent Malignant Glioma: A North American Brain Tumor Consortium… 
2011
2011
AMD3100 for urgent PBSC mobilization and allogeneic transplantation from a normal donor after failed marrow harvest
AMD3100 for urgent PBSC mobilization and allogeneic transplantation from a normal donor after failed marrow harvest 
2011
2011
Importance of Receptor Flexibility in Binding of Cyclam Compounds to the Chemokine Receptor CXCR4
We have elucidated the binding sites of four moncyclam and one bicyclam antagonist AMD3100, in the human chemokine receptor CXCR4… 
2009
2009
Stem-cell collection before high-dose therapy for multiple myeloma: time has come to raise the standards!
Stem-cell collection before high-dose therapy for multiple myeloma: time has come to raise the standards! 
2008
2008
Parasitology: Hopping mad
2007
2007
Inhibition of CXCR 4-Mediated Breast Cancer Metastasis : APotential Role for Heparinoids ?
Purpose: The pattern of breast cancer metastasis may be determined by interactions between CXCR4 on breast cancer cells and… 
2006
2006
CXCR4/SDF-1 Is a Key Regulator for Leukemia Migration and Homing to the BM: Impact of AMD3100 on In Vivo Response to Chemotherapy.
Hematopoietic stem cells (HSC) reside in the bone marrow (BM) and interact with stroma cells and extracellular matrix. CXCR4/SDF… 
2005
2005
Allograft Cell Content and GVHD Differ in Murine Recipients of AMD3100 Versus G-CSF Mobilized Peripheral Blood Stem Cells.
G-CSF is currently the preferred agent to mobilize peripheral blood stem cells (PBSC) for allogeneic hematopoietic cell… 
2000
2000
Anti-HIV agents. AMD-3100--chemokine blocker under study.