Plerixafor

Known as: 1,1'-[1,4-Phenylenebis(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane, Bis(Tetraazacyclotetradecane) Derivative 
A drug used before autologous stem cell transplantation in patients with non-Hodgkin lymphoma or multiple myeloma. Plerixafor is given together with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Blood neutrophil homeostasis is essential for successful host defense against invading pathogens. Circulating neutrophil counts… (More)
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Highly Cited
2012
Highly Cited
2012
The interaction of acute myeloid leukemia (AML) blasts with the leukemic microenvironment is postulated to be an important… (More)
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Highly Cited
2011
Highly Cited
2011
Plerixafor was recently approved by the US Food and Drug Administration (FDA) and the European Medicines Evaluation Agency (EMEA… (More)
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2011
2011
BACKGROUND Plerixafor is a recently Food and Drug Administration (FDA)-approved CXCR4 antagonist, which is combined with… (More)
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Review
2010
Review
2010
Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane… (More)
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Highly Cited
2009
Highly Cited
2009
This phase 3, multicenter, randomized (1:1), double-blind, placebo-controlled study evaluated the safety and efficacy of… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE This study evaluates the safety and efficacy of plerixafor (AMD3100), a CXCR4 antagonist, in mobilizing hematopoietic… (More)
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Review
2009
Review
2009
Hematopoietic and epithelial cancer cells express CXCR4, a seven-transmembrane G-protein-coupled chemokine receptor. Stromal… (More)
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2009
2009
Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize peripheral blood stem cells by different… (More)
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Highly Cited
2008
Highly Cited
2008
The purpose of this article was to examine historic institutional autologous stem cell mobilization practices and evaluate… (More)
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