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AM336

Known as: AM 336, AM-336, CVID, calcium channel blocker 
National Institutes of Health

Papers overview

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2015
2015
Venomous marine cone snails produce a unique and remarkably diverse range of venom peptides (conotoxins and conopeptides) that… Expand
2013
2013
BackgroundAntagonists of N-type voltage-gated calcium channels (VGCC), Cav2.2, can manage severe chronic pain with intrathecal… Expand
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2013
2013
Racemic [(±)-4-isopropyl-1-methyl-7-oxa-cis-bicyclo[4.3.0]non-4-en-8-one] and optically active δ,ε-unsaturated lactones [(-)-(1R… Expand
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2011
2011
OBJECTIVE Leconotide (CVID, AM336, CNSB004) is an omega conopeptide similar to ziconotide, which blocks voltage sensitive calcium… Expand
Review
2008
Review
2008
Background.  Expert panels of physicians and nonphysicians, all expert in intrathecal (IT) therapies, convened in the years 2000… Expand
2005
2005
Peptide toxins that selectively block voltage sensitive calcium channels have contributed enormously to our understanding of the… Expand
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2004
2004
Cone snails (Conidae) are marine predators with some extraordinary features. Their venom contains a hundred or more peptides that… Expand
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2003
2003
A liquid chromatography/mass spectrometry (LC/MS) analytical procedure, using a single column for sample clean-up, enrichment and… Expand
Highly Cited
2002
Highly Cited
2002
Agents which decrease conductance of N-type voltage-gated Ca(2+) channels have been shown to attenuate measures of neuropathic… Expand
Highly Cited
2002
Highly Cited
2002
&NA; N‐type calcium channels modulate the release of key pro‐nociceptive neurotransmitters such as glutamate and substance P (SP… Expand
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