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ALZHEIMER DISEASE 4

Known as: Familial Alzheimer Disease, Type 4, Alzheimer Disease, Familial, 4, Familial Alzheimer's Disease, Type 4 
Alzheimer's disease with an early onset (starts before the age of 65). It is caused by mutations in the PSEN2 gene.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Alzheimer's Disease
Autosomal dominant inheritanceCentral Nervous SystemNervous system structurePSEN2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Human adenovirus infections: update and consideration of mechanisms of viral persistence
Purpose of review To provide an update on recent studies of human adenoviral (HAdV) infections and to explore the mechanisms of… 
Highly Cited
2006
Highly Cited
2006
Two-Step Regulation of Ad4BP/SF-1 Gene Transcription during Fetal Adrenal Development: Initiation by a Hox-Pbx1-Prep1 Complex and Maintenance via Autoregulation by Ad4BP/SF-1
ABSTRACT The orphan nuclear receptor Ad4BP/SF-1 (adrenal 4 binding protein/steroidogenic factor 1) is essential for the proper… 
Highly Cited
2004
Highly Cited
2004
A low molecular weight copper chelator crosses the blood–brain barrier and attenuates experimental autoimmune encephalomyelitis
Increasing evidence suggests that enhanced production of reactive oxygen species (ROS) activates the MAP kinases, c‐Jun N… 
Review
2004
Review
2004
A two decade survey of respiratory adenovirus in Taiwan: The reemergence of adenovirus types 7 and 4
From November 1999 to December 2001, three outbreaks of adenovirus (Ad) respiratory infection occurred in southern Taiwan. To… 
Highly Cited
2002
Highly Cited
2002
Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1.
11beta-Hydroxylase (hCYP11B1) and aldosterone synthase (hCYP11B2) are closely related isozymes with distinct roles in cortisol… 
Highly Cited
1996
Highly Cited
1996
"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype.
Recombinant, replication-deficient adenovirus (Ad) vectors have been successfully used to transfer and express the normal human… 
Review
1995
Review
1995
Gene regulation of steroidogenesis
Highly Cited
1993
Highly Cited
1993
Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP.
We have examined the transcriptional activity of four cis-elements, Ad1(CRE), Ad2, Ad3, and Ad4, that are present in the promoter… 
Highly Cited
1992
Highly Cited
1992
A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s.
Highly Cited
1990
Highly Cited
1990
Novel cAMP regulatory elements in the promoter region of bovine P-450(11 beta) gene.
In order to elucidate the cAMP regulatory elements in the promoter region of bovine P-450(11 beta) genes, we analyzed the… 
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