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ALX 1393

Known as: ALX-1393, ALX1393 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Serine
analogs & derivatives

Papers overview

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2015
2015
Antinociceptive effect of intracerebroventricular administration of glycine transporter-2 inhibitor ALX1393 in rat models of inflammatory and neuropathic pain
2015
2015
Molecular Basis for Substrate and Inhibitor Interactions with the Glycine Transporter, GlyT2
The glycine transporter GlyT2 regulates synaptic glycine concentrations to control inhibitory neurotransmission. We aim to… 
2013
2013
Reversible inhibition of the glycine transporter GlyT2 circumvents acute toxicity while preserving efficacy in the treatment of pain
Available medications for chronic pain provide only partial relief and often cause unacceptable side effects. There is therefore… 
2013
2013
ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn
2011
2011
Pharmacological Characterization of [3H]CHIBA-3007 Binding to Glycine Transporter 1 in the Rat Brain
Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist… 
2011
2011
Glycine receptors influence radial migration in the embryonic mouse neocortex
To investigate whether glycine receptors influence radial migration in the neocortex, we analyzed the effect of glycine and the… 
2011
2011
The antinociceptive effect of intrathecal administration of glycine transporter-2 inhibitor ALX1393 in a rat acute pain model
2010
2010
N‐arachidonyl‐glycine modulates synaptic transmission in superficial dorsal horn
BACKGROUND AND PURPOSE The arachidonyl‐amino acid N‐arachidonyl‐glycine (NAGly) is an endogenous lipid, generated within the… 
2005
2005
Inhibitors of GlyT1 and GlyT2 differentially modulate inhibitory transmission
The chronic effects of glycine transporter 1 and 2 inhibitors (sarcosine and ALX-1393, respectively) on miniature inhibitory… 
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