ALX-0061
National Institutes of Health
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IntroductionThe pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the pathogenesis of different diseases…
Background ALX-0061 is a monovalent IL-6R targeting Nanobody, inhibiting signaling via soluble and membrane IL-6R. The safety…
Regulators have backed Janssen’s first-in-class, anti-interleukin-6 (IL-6) Sylvant (siltuximab) for multicentric Castleman’s…
Background ALX-0061 is a monovalent IL-6R targeting Nanobody. It inhibits signalling via soluble and membrane IL-6R. PK/PD…
Background Interleukin-6 (IL-6) is a pleiotropic cytokine inducing a wide range of biological activities via its receptor, which…