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ALVAC vaccine

Known as: ALVAC 
A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can't replicate. Thus, it produces a self-limiting infection which does… 
National Institutes of Health

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Viral Vaccines

Papers overview

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Highly Cited
2014
Highly Cited
2014
Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines
RV144 vaccination induced polyfunctional antibody Fc-effector responses, whereas VAX003 vaccination increased inhibitory IgG4… 
Highly Cited
2008
Highly Cited
2008
A West Nile virus (WNV) recombinant canarypox virus vaccine elicits WNV-specific neutralizing antibodies and cell-mediated immune responses in the horse.
Highly Cited
2008
Highly Cited
2008
Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer
Purpose: The combination of vaccines and chemotherapy holds promise for cancer therapy, but the effect of cytotoxic chemotherapy… 
Review
2007
Review
2007
Development and registration of recombinant veterinary vaccines. The example of the canarypox vector platform.
Highly Cited
2001
Highly Cited
2001
Polymorphisms in HLA Class I Genes Associated with both Favorable Prognosis of Human Immunodeficiency Virus (HIV) Type 1 Infection and Positive Cytotoxic T-Lymphocyte Responses to ALVAC-HIV…
ABSTRACT Carriers of certain human leukocyte antigen class I alleles show favorable prognosis of human immunodeficiency virus… 
Highly Cited
2000
Highly Cited
2000
Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory molecule
Abstract The generation of cytotoxic effector T cells requires delivery of two signals, one derived from a specific antigenic… 
Highly Cited
1997
Highly Cited
1997
Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers.
A fundamental goal of current strategies to develop an efficacious vaccine for AIDS is the elicitation of broadly reactive… 
Highly Cited
1997
Highly Cited
1997
Canine distemper virus (CDV) infection of ferrets as a model for testing Morbillivirus vaccine strategies: NYVAC- and ALVAC-based CDV recombinants protect against symptomatic infection
Canine distemper virus (CDV) infection of ferrets causes an acute systemic disease involving multiple organ systems, including… 
Highly Cited
1996
Highly Cited
1996
Human safety and immunogenicity of a canarypox-rabies glycoprotein recombinant vaccine: an alternative poxvirus vector system.
Highly Cited
1993
Highly Cited
1993
Protection of cats against feline leukemia virus by vaccination with a canarypox virus recombinant, ALVAC-FL
Two ALVAC (canarypox virus)-based recombinant viruses expressing the feline leukemia virus (FeLV) subgroup A env and gag genes… 
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