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Dual-subtype FIV vaccine protects cats against in vivo swarms of both homologous and heterologous subtype FIV isolates
ObjectiveTo evaluate the immunogenicity and efficacy of an inactivated dual-subtype feline immunodeficiency virus (FIV) vaccine. DesignSpecific-pathogen-free cats were immunized with dual-subtype… Expand
Feline immunodeficiency virus pathogenesis and development of a dual-subtype feline-immunodeficiency-virus vaccine.
IntroductionFeline immunodeficiency virus (FIV) infection is a natural infection of domestic felid populations which results in a chronic and progressive acquired immunodeficiency syndrome [1–3]. FIV… Expand
Immunohistochemical and in situ hybridization studies of gonadotropin releasing hormone (GnRH) and its receptor in rat digestive tract.
GnRH(LH-RH) is first discovered in the hypothalamus and found to have a role in regulation of reproduction. With the study on it deepening, GnRH was demonnstrated that it also exists in a number of… Expand
Superinfection of cats with feline immunodeficiency virus subtypes A and B.
- S. Okada, R. Pu, Elisabeth Young, W. V. Stoffs, J. Yamamoto
- Biology, Medicine
- AIDS research and human retroviruses
- 1 December 1994
The ability of feline immunodeficiency virus (FIV) isolates from subtypes A and B to superinfect cats and cell cultures was tested. Three specific pathogen-free (SPF) cats were first inoculated with… Expand
Experimental vaccine protection against homologous and heterologous strains of feline immunodeficiency virus.
More than 90% of cats immunized with inactivated whole infected-cell or cell-free feline immunodeficiency virus (FIV) vaccines were protected against intraperitoneal infection with 10 50% animal… Expand
FIV vaccine development and its importance to veterinary and human medicine: a review
- E. Uhl, T. Heaton-Jones, R. Pu, J. Yamamoto
- Medicine, Biology
- Veterinary Immunology and Immunopathology
- 8 October 2002
Abstract Feline immunodeficiency virus (FIV) is a natural infection of domestic cats that results in acquired immunodeficiency syndrome resembling human immunodeficiency virus (HIV) infection in… Expand
Dual-subtype FIV vaccine (Fel-O-Vax® FIV) protection against a heterologous subtype B FIV isolate
- R. Pu, J. Coleman, +4 authors J. Yamamoto
- Biology, Medicine
- Journal of feline medicine and surgery
- 1 February 2005
Vaccine trials were undertaken to determine whether the Fel-O-Vax® FIV, a commercial dual-subtype (subtypes A and D) feline immunodeficiency virus (FIV) vaccine, is effective against a subtype B FIV… Expand
Cellular immune responses to feline immunodeficiency virus (FIV) induced by dual-subtype FIV vaccine.
Vaccine-induced T cell responses to FIV were assessed by measuring FIV-specific cytokine and cytotoxic-effector molecule production. A total of 22 cats at 10-12 weeks of age received either… Expand
Efficacy evaluation of prime–boost protocol: canarypoxvirus‐based feline immunodeficiency virus (FIV) vaccine and inactivated FIV‐infected cell vaccine against heterologous FIV challenge in cats
Objective:To evaluate the immunogenicity and prophylactic efficacy of immunization schemes employing a recombinant canarypoxvirus (‘ALVAC’)-based feline immunodeficiency virus (FIV) vaccine alone or… Expand
HIV-1 p24 vaccine protects cats against feline immunodeficiency virus infection
Background:Based on previous analysis of feline immunodeficiency virus (FIV)-specific cross-reactive antibodies to HIV-1 p24, cats vaccinated with HIV-1 p24 were evaluated for cross-reactive immunity… Expand