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ALKBH8 gene

Known as: ABH8, alkB homolog 8, tRNA methyltransferase, MGC10235 
 
National Institutes of Health

Papers overview

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2015
2015
Environmental and metabolic sources of reactive oxygen species (ROS) can damage DNA, proteins and lipids to promote disease… Expand
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Review
2014
Review
2014
tRNA modifications are crucial for efficient and accurate protein translation, with defects often linked to disease. There are 7… Expand
Highly Cited
2011
Highly Cited
2011
Background Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the… Expand
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Highly Cited
2011
Highly Cited
2011
Mammals have nine different homologues (ALKBH1-9) of the Escherichia coli DNA repair demethylase AlkB. ALKBH2 is a genuine DNA… Expand
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2011
2011
Uridine at the wobble position of tRNA is usually modified, and modification is required for accurate and efficient protein… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT Uridines in the wobble position of tRNA are almost invariably modified. Modifications can increase the efficiency of… Expand
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Highly Cited
2010
Highly Cited
2010
The ABH8 protein (also called ALKBH8) is a member of the AlkB (alkylated DNA repair protein) family of nonheme iron… Expand
Highly Cited
2009
Highly Cited
2009
We recently identified a novel human AlkB homologue, ALKBH8, which is expressed in various types of human cancers including human… Expand
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Highly Cited
2008
Highly Cited
2008
Modification of Saccharomyces cerevisiae tRNA anticodons at the wobble uridine (U34) position is required for tRNA cleavage by… Expand
Highly Cited
2006
Highly Cited
2006
Zymocin‐induced cell death in Saccharomyces cerevisiae requires the toxin‐target (TOT) effector Elongator, a protein complex with… Expand