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ALKBH2 gene

Known as: ABH2, AlkB, E. COLI, HOMOLOG OF, 2, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase 
National Institutes of Health

Papers overview

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2017
2017
Cancer-associated mutations often lead to perturbed cellular energy metabolism and accumulation of potentially harmful… Expand
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Highly Cited
2012
Highly Cited
2012
More than 15% of cancer deaths worldwide are associated with underlying infections or inflammatory conditions, therefore… Expand
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2012
2012
ALKBH2 is a direct DNA repair dioxygenase guarding the mammalian genome against N1-methyladenine, N3-methylcytosine and 1,N6… Expand
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Highly Cited
2010
Highly Cited
2010
The ABH8 protein (also called ALKBH8) is a member of the AlkB (alkylated DNA repair protein) family of nonheme iron… Expand
Highly Cited
2009
Highly Cited
2009
Iron- and 2-oxoglutarate-dependent dioxygenases are a diverse family of non-heme iron enzymes that catalyze various important… Expand
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Highly Cited
2008
Highly Cited
2008
Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation… Expand
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Highly Cited
2008
Highly Cited
2008
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenine (epsilon A) originates from lipid peroxidation. Elevated… Expand
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Highly Cited
2005
Highly Cited
2005
Human and Escherichia coli derivatives of AlkB enzymes remove methyl groups from 1-methyladenine and 3-methylcytosine in nucleic… Expand
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Highly Cited
2003
Highly Cited
2003
The Escherichia coli AlkB protein, and two human homologs ABH2 and ABH3, directly demethylate 1-methyladenine and 3… Expand
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Highly Cited
2002
Highly Cited
2002
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the DNA lesions 1… Expand
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