FAQ

ALKBH2 gene

Known as: ABH2, AlkB, E. COLI, HOMOLOG OF, 2, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase 
 

Topic mentions per year

Topic mentions per year

2002-2017
02420022017

Papers overview

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2015
2015
Emulsion PCR significantly improves nonequilibrium capillary electrophoresis of equilibrium mixtures-based aptamer selection: allowing for efficient and rapid selection of aptamer to unmodified ABH2…
Nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM), a homogeneous approach to select DNA aptamers, is… (More)
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2013
2013
ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.
The ALKBH family of proteins are highly expressed in various types of human cancer where they are involved in tumor growth and… (More)
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2013
2013
The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.
INTRODUCTION Glioblastoma multiforme (GBM; World Health Organization astrocytoma grade IV) is the most frequent and most… (More)
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2012
2012
Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase.
Exocyclic ethenobases are highly mutagenic DNA lesions strongly implicated in inflammation and vinyl chloride-induced… (More)
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2010
2010
Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers.
Iron- and 2-oxoglutarate-dependent dioxygenases are a diverse family of non-heme iron enzymes that catalyze various important… (More)
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2009
2009
A non-heme iron-mediated chemical demethylation in DNA and RNA.
DNA methylation is arguably one of the most important chemical signals in biology. However, aberrant DNA methylation can lead to… (More)
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2008
2008
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation… (More)
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2008
2008
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenine (epsilon A) originates from lipid peroxidation. Elevated… (More)
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2003
2003
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase.
The Escherichia coli AlkB protein, and two human homologs ABH2 and ABH3, directly demethylate 1-methyladenine and 3… (More)
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Highly Cited
2002
Highly Cited
2002
Reversal of DNA alkylation damage by two human dioxygenases.
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the DNA lesions 1… (More)
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