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ALKBH2 gene
Known as:
ABH2
, AlkB, E. COLI, HOMOLOG OF, 2
, alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions.
Fangyi Chen
,
Ke Bian
,
+5 authors
Deyu Li
Chemical research in toxicology
2017
Corpus ID: 206532240
Cancer-associated mutations often lead to perturbed cellular energy metabolism and accumulation of potentially harmful…
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Highly Cited
2015
Highly Cited
2015
Emulsion PCR significantly improves nonequilibrium capillary electrophoresis of equilibrium mixtures-based aptamer selection: allowing for efficient and rapid selection of aptamer to unmodified ABH2…
Roman Yufa
,
S. Krylova
,
C. Bruce
,
Eleanor A. L. Bagg
,
C. Schofield
,
S. Krylov
Analytical chemistry
2015
Corpus ID: 9239667
Nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM), a homogeneous approach to select DNA aptamers, is…
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Highly Cited
2012
Highly Cited
2012
DNA repair is indispensable for survival after acute inflammation.
J. Calvo
,
L. Meira
,
+8 authors
L. Samson
The Journal of clinical investigation
2012
Corpus ID: 8095130
More than 15% of cancer deaths worldwide are associated with underlying infections or inflammatory conditions, therefore…
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Highly Cited
2012
Highly Cited
2012
Duplex Interrogation by a Direct DNA Repair Protein in Search of Base Damage
C. Yi
,
Baoen Chen
,
+7 authors
Chuan He
Nature Structural &Molecular Biology
2012
Corpus ID: 15021142
ALKBH2 is a direct DNA repair dioxygenase guarding the mammalian genome against N1-methyladenine, N3-methylcytosine and 1,N6…
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Highly Cited
2010
Highly Cited
2010
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
Ye Fu
,
Qing Dai
,
Wen Zhang
,
Jinghe Ren
,
T. Pan
,
Chuan He
Angewandte Chemie
2010
Corpus ID: 1922240
The ABH8 protein (also called ALKBH8) is a member of the AlkB (alkylated DNA repair protein) family of nonheme iron…
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Highly Cited
2009
Highly Cited
2009
Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers*
Haobin Chen
,
N. C. Giri
,
+4 authors
Max Costa
The Journal of Biological Chemistry
2009
Corpus ID: 19987543
Iron- and 2-oxoglutarate-dependent dioxygenases are a diverse family of non-heme iron enzymes that catalyze various important…
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Highly Cited
2008
Highly Cited
2008
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Cai-Guang Yang
,
C. Yi
,
+4 authors
Chuan He
Nature
2008
Corpus ID: 4393864
Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation…
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Highly Cited
2008
Highly Cited
2008
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.
J. Ringvoll
,
M. N. Moen
,
+8 authors
A. Klungland
Cancer research
2008
Corpus ID: 26367996
Endogenous formation of the mutagenic DNA adduct 1,N(6)-ethenoadenine (epsilon A) originates from lipid peroxidation. Elevated…
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Highly Cited
2005
Highly Cited
2005
Repair of Methylation Damage in DNA and RNA by Mammalian AlkB Homologues*
Dong-Hyun Lee
,
Seung-Gi Jin
,
S. Cai
,
Yuan Chen
,
G. Pfeifer
,
T. O'Connor
Journal of Biological Chemistry
2005
Corpus ID: 23792925
Human and Escherichia coli derivatives of AlkB enzymes remove methyl groups from 1-methyladenine and 3-methylcytosine in nucleic…
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Highly Cited
2002
Highly Cited
2002
Reversal of DNA alkylation damage by two human dioxygenases
T. Duncan
,
S. Trewick
,
P. Koivisto
,
P. Bates
,
T. Lindahl
,
B. Sedgwick
Proceedings of the National Academy of Sciences…
2002
Corpus ID: 32107873
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the DNA lesions 1…
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