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ALDH1A1 gene

Known as: ALDEHYDE DEHYDROGENASE 1, ALDH1, retinaldehyde dehydrogenase 1 
This gene is involved in the metabolism of retinal.
National Institutes of Health

Related topics

Related topics

7 relations
ALDH18A1 geneALDH1A1 protein, humanALDH1L2 geneEthanol Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer.
Highly Cited
2012
Highly Cited
2012
Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer
Gastric cancer (GC) is one of the most common malignancies worldwide. Recently, cancer stem cells (CSCs) in tumors were found to… 
Highly Cited
2012
Highly Cited
2012
Tumorigenesis and Neoplastic Progression ALDH 1-Bright Epithelial Ovarian Cancer Cells Are Associated with CD 44 Expression , Drug Resistance , and Poor Clinical Outcome
The role of aldehyde dehydrogenase 1 (ALDH1) as an ovarian cancer stem cell marker and its clinical significance have rarely been… 
Highly Cited
2010
Highly Cited
2010
Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity.
Glioblastoma (GBM) is the most aggressive primary brain tumor and is resistant to all therapeutic regimens. Relapse occurs… 
Highly Cited
2010
Highly Cited
2010
Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
A relatively rare aldehyde dehydrogenase 1 (ALDH1)-positive "stem cell-like" subpopulation of tumor cells has the unique ability… 
Highly Cited
2008
Highly Cited
2008
ALDH1A1 and ALDH3A1 expression in lung cancers: correlation with histologic type and potential precursors.
Highly Cited
2005
Highly Cited
2005
Cancer stem cell characteristics in retinoblastoma.
PURPOSE There is increasing evidence that cancer stem cells contribute to tumor progression and chemoresistance in a variety of… 
Highly Cited
2002
Highly Cited
2002
Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study
Abstract.Purpose: In preclinical models, established molecular determinants of cellular sensitivity to cyclophosphamide, long a… 
Highly Cited
1998
Highly Cited
1998
Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases.
Highly Cited
1985
Highly Cited
1985
Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2.
Partial cDNA clones encoding human cytosolic aldehyde dehydrogenase (ALDH1) and mitochondrial aldehyde dehydrogenase (ALDH2) were… 
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