AL 34662

Known as: AL-34662, AL34662 
 
National Institutes of Health

Papers overview

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2017
2017
Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor.
BACKGROUND AND PURPOSE Visceral hypersensitivity is responsible for pathogenesis of irritable bowel syndrome (IBS). Therefore… (More)
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2015
2015
Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist.
Recently, it has been reported that 5-HT2 receptor agonists effectively reduce intraocular pressure (IOP) in a nonhuman primate… (More)
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Review
2010
Review
2010
Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action.
The eye is innervated by numerous serotonergic nerves and serotonin (5-hydroxytryptamine; 5HT) is present in the aqueous humor of… (More)
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2008
2008
Two-step N-acylindazole to N-alkylindazole reduction. Further synthetic studies on the serotonergic agonist AL-34662
 
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2007
2007
AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist.
PURPOSE AND METHODS The aim of this study was to determine the ocular pharmacological characteristics of AL-34662 (1-((S)-2… (More)
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2006
2006
Serotonin-2 (5-HT2) receptor-mediated signal transduction in human ciliary muscle cells: role in ocular hypotension.
PURPOSE AND METHODS The aim of this study was to characterize the serotonin (5-hydroxytryptamine; 5-HT) receptors that mediate… (More)
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