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AL 34662

Known as: AL-34662, AL34662 
National Institutes of Health

Papers overview

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2017
2017
Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5‐HT2A receptor
Visceral hypersensitivity is responsible for pathogenesis of irritable bowel syndrome (IBS). Therefore, its prevention can help… 
2015
2015
Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist.
Recently, it has been reported that 5-HT2 receptor agonists effectively reduce intraocular pressure (IOP) in a nonhuman primate… 
Review
2010
Review
2010
Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action.
  • N. Sharif
  • Current Drug Targets
  • 2010
  • Corpus ID: 43715352
The eye is innervated by numerous serotonergic nerves and serotonin (5-hydroxytryptamine; 5HT) is present in the aqueous humor of… 
2007
2007
AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist.
PURPOSE AND METHODS The aim of this study was to determine the ocular pharmacological characteristics of AL-34662 (1-((S)-2… 
2006
2006
Serotonin-2 (5-HT2) receptor-mediated signal transduction in human ciliary muscle cells: role in ocular hypotension.
PURPOSE AND METHODS The aim of this study was to characterize the serotonin (5-hydroxytryptamine; 5-HT) receptors that mediate… 
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