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AL 34662
Known as:
AL-34662
, AL34662
National Institutes of Health
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2017
2017
Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5‐HT2A receptor
Teita Asano
,
Ken-ichiro Tanaka
,
+5 authors
M. Takenaga
British Journal of Pharmacology
2017
Corpus ID: 43604389
Visceral hypersensitivity is responsible for pathogenesis of irritable bowel syndrome (IBS). Therefore, its prevention can help…
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2015
2015
Ocular Hypotensive Response in Nonhuman Primates of (8R)-1-[(2S)-2-Aminopropyl]-8,9-dihydro-7H-pyrano[2,3-g]indazol-8-ol a Selective 5-HT2 Receptor Agonist.
J. May
,
N. Sharif
,
+8 authors
T. Dean
Journal of Medicinal Chemistry
2015
Corpus ID: 33310754
Recently, it has been reported that 5-HT2 receptor agonists effectively reduce intraocular pressure (IOP) in a nonhuman primate…
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Review
2010
Review
2010
Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action.
N. Sharif
Current Drug Targets
2010
Corpus ID: 43715352
The eye is innervated by numerous serotonergic nerves and serotonin (5-hydroxytryptamine; 5HT) is present in the aqueous humor of…
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2007
2007
AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist.
N. Sharif
,
M. Mclaughlin
,
C. Kelly
Journal of Ocular Pharmacology and Therapeutics
2007
Corpus ID: 44927988
PURPOSE AND METHODS The aim of this study was to determine the ocular pharmacological characteristics of AL-34662 (1-((S)-2…
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2006
2006
Serotonin-2 (5-HT2) receptor-mediated signal transduction in human ciliary muscle cells: role in ocular hypotension.
N. Sharif
,
C. Kelly
,
J. Crider
,
T. Davis
Journal of Ocular Pharmacology and Therapeutics
2006
Corpus ID: 8120401
PURPOSE AND METHODS The aim of this study was to characterize the serotonin (5-hydroxytryptamine; 5-HT) receptors that mediate…
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