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AKAP11 gene

Known as: A-kinase anchoring protein 11, AKAP 220, A-kinase anchoring protein, 220kDa 
 
National Institutes of Health

Papers overview

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2016
2016
AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.
Filtration through the kidney eliminates toxins, manages electrolyte balance, and controls water homeostasis. Reabsorption of… Expand
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2014
2014
PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation
cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA… Expand
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2012
2012
Genome-wide association analysis of Sasang constitution in the Korean population.
OBJECTIVES Sasang constitutional medicine is a traditional Korean medicine in which an individual is classified into one of four… Expand
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2011
2011
Isoform-specific targeting of PKA to multivesicular bodies
Although RII protein kinase A (PKA) regulatory subunits are constitutively localized to discrete cellular compartments through… Expand
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2008
2008
AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts.
During dehydration, protein kinase A phosphorylates aquaporin 2 (AQP2) at serine 256 and this is essential for apical membrane… Expand
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2008
2008
GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220.
In our previous study, anti-apoptotic effects of GABA(C)-receptor stimulation was suppressed by inhibitors of cAMP-dependent… Expand
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Highly Cited
2002
Highly Cited
2002
A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta.
Glycogen synthase kinase-3 (GSK-3) is regulated by various extracellular ligands and phosphorylates many substrates, thereby… Expand
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2001
2001
Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation.
The phosphorylation status of cellular proteins is controlled by the opposing actions of protein kinases and phosphatases… Expand
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Highly Cited
2000
Highly Cited
2000
Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis.
Using a combination of protein kinase A type II overlay screening, rapid amplification of cDNA ends, and database searches, a… Expand
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Highly Cited
1999
Highly Cited
1999
Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220
The cyclic AMP (cAMP)-dependent protein kinase (PKA) and the type 1 protein phosphatase (PP1) are broad-specificity signaling… Expand
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