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AK 295

Known as: AK-295, AK295, Carbamic acid, (1-(((1-ethyl-3-((3-(4-morpholinyl)propyl)amino)-2,3-dioxopropyl)amino)carbonyl)-3-methylbutyl)-, phenylmethyl ester, stereoisomer 
National Institutes of Health

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Dipeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Calpain inhibitor AK 295 inhibits calpain-induced apoptosis and damage in rat kidney
Objectives: In the present investigation, the effect of a calpain inhibitor, AK 295, on ischemia/ reperfusion damage in rat… 
2011
2011
Noise , Calpain , Calpain Inhibitors , and Neuroprotection : A Preliminary Report of Tinnitus Control
Frequently, noise-induced hearing loss is associated with the symptom of tinnitus. Preliminary results in the animal model after… 
2010
2010
Evaluation of the effect of calpain inhibitor AK295 on paclitaxel-induced neuropathy and antitumor activity in human cancer xenograft models.
e13510 Background: Paclitaxel is a chemotherapeutic agent that induces apoptosis of tumor cells in several cancer types including… 
2009
2009
Anti-GD1a antibody targeted disruption of the node of Ranvier in a mouse model of acute motor axonal neuropathy
Guillain-Barre syndrome (GBS) is a peripheral neuropathy characterised by acute flaccid paralysis. The axonal variant is… 
Highly Cited
2000
Highly Cited
2000
Behavioral Efficacy of Posttraumatic Calpain Inhibition is Not Accompanied by Reduced Spectrin Proteolysis, Cortical Lesion, or Apoptosis
Administration of the selective calpain inhibitor AK295 has been shown to attenuate motor and cognitive dysfunction after brain… 
2000
2000
Comparison of various calpain inhibitors in reduction of light scattering, protein precipitation and nuclear cataract in vitro
Purpose. To compare effects of calpain inhibitors on in vitro light-scattering in rat lens soluble protein and calcium-ionophore… 
1998
1998
New inhibitors of calpain prevent degradation of cytoskeletal and myelin proteins in spinal cord in vitro
We have determined the effects of the calpain inhibitors AK275 and AK295 upon purified m‐calpain and calcium‐mediated degradation… 
1998
1998
Noise, Calpain, Calpain Inhibitors, and Neuroprotection: A Preliminary Report of Tinnitus Control.
Frequently, noise-induced hearing loss is associated with the symptom of tinnitus. Preliminary results in the animal model after… 
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