Skip to search formSkip to main contentSkip to account menu

AIM2 wt Allele

Known as: AIM2, Absent In Melanoma 2 wt Allele, Absent in Melanoma 2 
Human AIM2 is located in the vicinity of 1q22 and is approximately 40 kb in length. This gene, which encodes membrane-associated transporter protein… 
National Institutes of Health

Related topics

Related topics

6 relations
1q22AIM2 geneAbsent in melanoma 2 proteinCell Cycle Control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Involvement of NLRC4 inflammasome through caspase-1 and IL-1β augments neuroinflammation and contributes to memory impairment in an experimental model of Alzheimer's like disease
2019
2019
Inflammasome and cytokine expression profiling in experimental periodontitis in the integrin &bgr;6 null mouse
2018
2018
Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection.
Highly Cited
2016
Highly Cited
2016
Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway
Absent in melanoma (AIM2) is a member of the interferon-inducible HIN-200 protein family and is recently recognized to play an… 
Review
2016
Review
2016
The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection
The innate immune system is essential for the detection and elimination of bacterial pathogens. Upon inflammasome activation… 
Highly Cited
2014
Highly Cited
2014
AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18
Background & Aims. AIM2 plays an important role in innate immunity, but its role in regulating the immune response to hepatitis B… 
Review
2014
Review
2014
The roles of interferon-inducible p200 family members IFI16 and p204 in innate immune responses, cell differentiation and proliferation
2014
2014
The Microtubule-associated Protein EB1 Links AIM2 Inflammasomes with Autophagy-dependent Secretion*
Background: Following AIM2 inflammasome activation, EB1 is required for speck formation. Results: EB1 regulates AIM2 inflammasome… 
Highly Cited
2012
Highly Cited
2012
Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia
TET2 enzymatically converts 5-methyl-cytosine to 5-hydroxymethyl-cytosine, possibly leading to loss of DNA methylation. TET2… 
Highly Cited
2000
Highly Cited
2000
Cytoplasmic localization of the interferon‐inducible protein that is encoded by the AIM2 (absent in melanoma) gene from the 200‐gene family
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)