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AIM2 wt Allele

Known as: AIM2, Absent In Melanoma 2 wt Allele, Absent in Melanoma 2 
Human AIM2 is located in the vicinity of 1q22 and is approximately 40 kb in length. This gene, which encodes membrane-associated transporter protein… 
National Institutes of Health

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1q22AIM2 geneAbsent in melanoma 2 proteinCell Cycle Control

Papers overview

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2019
2019
Función del inflamasoma AIM2 en el desarrollo de carcinoma hepatocelular
La inflamacion hepatica cronica es un fenomeno crucial en la patogenesis del carcinoma hepatocelular (HCC). En los ultimos anos… 
2018
2018
Inflammasome activity in the inflammatory bowel diseases
Ulcerative colitis (UC) and Crohn’s disease (CD) are characterised by chronic and recurrent inflammation of the gastrointestinal… 
2017
2017
Role of the inflammasome in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial pneumonia of unknown aetiology, characterized by progressive… 
2016
2016
Corrigendum: Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events
In the version of this Research Highlight initially published, only the work of Gao et al. (Proc. Natl. Acad. Sci. USA 112, 12903… 
2015
2015
GBPs take AIM at Francisella
Guanylate-binding proteins (GBPs) induced by type I interferon signaling cause lysis of Francisella bacteria that have reached… 
2015
2015
Rôle de l'inflammasome NLRP3 dans l'athérosclérose et le diabète de type 2
L’inflammasome NLRP3, un complexe proteique pro-inflammatoire, joue un role essentiel dans le processus pathologique de l… 
2015
2015
OP0085 The Patients with Primary Sjögren's Syndrome Display Inflammasome Activation in the Peripheral Blood and the Salivary Glands that Correlates With Deficient Degradation of DNA
Background Inflammasomes are intracellular multiprotein complexes that sense pathogenic microorganisms, as well as DNA and other… 
2014
2014
NLRP3 and AIM2 mediate nitric oxide production and macrophage resistance to T. cruzi infection (INM3P.442)
The Toll-like receptors (TLRs), 2, 4 and 9 are important to immunity against Trypanosoma cruzi, etiologic agent of Chagas… 
2013
2013
The DNA sensing inflammasome, AIM2, is critical for protection from influenza infection (P6140)
Sensing of viral-derived nucleic acids following entry into cytosol of the host cell triggers inflammasome activation leading… 
2012
2012
Characterization of the immune response induced by non-pathogenic mycobacteria in macrophages and dendritic cells
Title of Document: CHARACTERIZATION OF THE IMMUNE RESPONSE INDUCED BY NON-PATHOGENIC MYCOBACTERIA IN MACROPHAGES AND DENDRITIC… 
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