AIM2 wt Allele

Known as: AIM2, Absent In Melanoma 2 wt Allele, Absent in Melanoma 2 
Human AIM2 is located in the vicinity of 1q22 and is approximately 40 kb in length. This gene, which encodes membrane-associated transporter protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
051019972017

Papers overview

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Highly Cited
2015
Highly Cited
2015
Colorectal cancer is a leading cause of cancer-related deaths. Mutations in the innate immune sensor AIM2 are frequently… (More)
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2015
2015
BACKGROUND Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gut, partly driven by defects in… (More)
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2014
2014
BACKGROUND & AIMS AIM2 plays an important role in innate immunity, but its role in regulating the immune response to hepatitis B… (More)
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Highly Cited
2013
Highly Cited
2013
Inflammasomes are protein complexes assembled upon recognition of infection or cell damage signals, and serve as platforms for… (More)
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2013
2013
Mycobacterium tuberculosis extracellular DNA gains access to the host cell cytosol via the ESX-1 secretion system. It is puzzling… (More)
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2013
2013
Innate immunity is the first line of defense against invasive microbial infection, and AIM2 plays an important role in this… (More)
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Highly Cited
2009
Highly Cited
2009
Cytoplasmic DNA triggers activation of the innate immune system. Although 'downstream' signaling components have been… (More)
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2005
2005
The human HIN-200 family member AIM2 was originally identified in a screen for suppressors of melanoma tumorigenicity following… (More)
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2000
2000
While interferons (IFNs) (alpha, beta and gamma), a family of cytokines, have the ability to exert the growth-inhibitory effect… (More)
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Highly Cited
1997
Highly Cited
1997
Chromosome 6-mediated suppression of tumorigenicity in malignant melanoma cell lines provides a model system to identify genes… (More)
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