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AH 6809

Known as: AH-6809, AH6809 
National Institutes of Health

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1 relation

Broader (1)

6-isopropoxy-9-oxoxanthene-2-carboxylic acid

Papers overview

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2010
2010
Prostaglandin E Receptor EP1 Suppresses Breast Cancer Metastasis and Is Linked to Survival Differences and Cancer Disparities
Cyclooxygenase-2 is frequently overexpressed and associated with poor prognosis in breast cancer. The cyclooxygenase-2 product… 
Highly Cited
2008
Highly Cited
2008
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
AIMS The present study examined the hypothesis that prostaglandin E2 (PGE2) through activation of prostaglandin E (EP) receptor… 
2005
2005
Phospholipase A2 activating protein (PLAA) is required for 1α,25(OH)2D3 signaling in growth plate chondrocytes
Phospholipase A2 (PLA2) is pivotal in the rapid membrane‐mediated actions of 1,25‐dihydroxyvitamin D3 [1α,25(OH)2D3]. Microarray… 
Highly Cited
2004
Highly Cited
2004
Vasoconstriction induced by activation of EP1 and EP3 receptors in human lung: effects of ONO-AE-248, ONO-DI-004, ONO-8711 or ONO-8713.
2003
2003
Functional prostaglandin E (EP) receptors in human penile corpus cavernosum
In this study, we have characterized functional EP receptors in human corpus cavernosum (HCC) tissue and in HCC smooth muscle… 
Highly Cited
2002
Highly Cited
2002
Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature.
Although isoprostanes generally act on smooth muscle via TXA(2)-selective prostanoid receptors (TPs), some suggest other… 
1997
1997
Prostaglandin E receptors in myometrial cells.
Prostaglandins (PGs) exert their effects via binding to specific cell surface receptors and influencing second messenger systems… 
Highly Cited
1992
Highly Cited
1992
Thermal and PGE2 sensitivity of the organum vasculosum lamina terminalis region and preoptic area in rat brain slices.
1. The effects of local applications of prostaglandin E2 (PGE2) on the unit activity of fifty‐one neurones in the organum… 
Highly Cited
1991
Highly Cited
1991
Role of the prostaglandin E2 receptor in mammary tumor metastasis.
Both clinical and experimental breast tumors often synthesize high levels of prostaglandins, most notably prostaglandin E2 (PGE2… 
Highly Cited
1991
Highly Cited
1991
Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype.
Corneal endothelial cells synthesize prostaglandin E2 (PGE2), and this synthesis is necessary for the maintenance of the normal… 
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