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AGTRAP gene

Known as: Angiotensin II Receptor-Associated Protein Gene, AGTRAP, angiotensin II receptor associated protein 
This gene plays a role in angiotensin signaling.
National Institutes of Health

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AGTRAP wt Allele
Receptor SignalingSignal TransductionType-1 Angiotensin II Receptor-Associated Proteinprotein protein interaction

Papers overview

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2019
2019
Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension
Background We have previously shown that ATRAP (angiotensin II receptor–associated protein; Agtrap) interacts with AT1R… 
2018
2018
Angiotensin II type 1 receptor-associated protein regulates carotid intimal hyperplasia through controlling apoptosis of vascular smooth muscle cells.
2017
2017
Effect of prehypertensive losartan therapy on AT1R and ATRAP methylation of adipose tissue in the later life of high-fat-fed spontaneously hypertensive rats
Hypertension is frequently associated with metabolic disorders. The present study was designed to investigate the long-term… 
2014
2014
Effects of Ang II Receptor Blocker Irbesartan on Adipose Tissue Function in Mice with Metabolic Disorders
Recent studies indicate that the functional renin-angiotensin system (RAS) exists in the adipose tissue. The adipose tissue RAS… 
2014
2014
Effects of the Angiotensin Receptor Blocker Olmesartan on Adipocyte Hypertrophy and Function in Mice with Metabolic Disorders
In the present study, we examined the therapeutic effects of olmesartan, an angiotensin II (Ang II) type 1 receptor (AT1R… 
2013
2013
Enhanced Angiotensin Receptor-Associated Protein in Renal Tubule Suppresses Angiotensin-Dependent Hypertension
We have previously shown that angiotensin II type 1 receptor-associated protein (ATRAP/Agtrap) interacts with the angiotensin II… 
2011
2011
Prepubertal angiotensin blockade exerts long-term therapeutic effect through sustained ATRAP activation in salt-sensitive hypertensive rats
Objective We previously showed that the molecule interacting with Ang II type 1 receptor (AT1R), ATRAP, promotes AT1R… 
2010
2010
Intrarenal suppression of angiotensin II type 1 receptor binding molecule in angiotensin II-infused mice.
ATRAP [ANG II type 1 receptor (AT1R)-associated protein] is a molecule which directly interacts with AT1R and inhibits AT1R… 
2010
2010
Expression of angiotensin II type 1 receptor-interacting molecule in normal human kidney and IgA nephropathy.
The intrarenal renin-angiotensin system plays a crucial role in the regulation of renal circulation and sodium reabsorption… 
2002
2002
Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap).
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