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AGTRAP gene

Known as: Angiotensin II Receptor-Associated Protein Gene, AGTRAP, angiotensin II receptor associated protein 
This gene plays a role in angiotensin signaling.
National Institutes of Health

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AGTRAP wt Allele
Receptor SignalingSignal TransductionType-1 Angiotensin II Receptor-Associated Proteinprotein protein interaction

Papers overview

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Highly Cited
2013
Highly Cited
2013
Identifying multiple causative genes at a single GWAS locus.
Genome-wide association studies (GWAS) are useful for nominating candidate genes, but typically are unable to establish disease… Expand
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2013
2013
Angiotensin Receptor–Binding Protein ATRAP/Agtrap Inhibits Metabolic Dysfunction With Visceral Obesity
BACKGROUND Metabolic disorders with visceral obesity have become a major medical problem associated with the development of… Expand
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Review
2011
Review
2011
Angiotensin II and the vascular phenotype in hypertension.
Hypertension is associated with vascular changes characterised by remodelling, endothelial dysfunction and hyperreactivity… Expand
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2011
2011
Prepubertal angiotensin blockade exerts long-term therapeutic effect through sustained ATRAP activation in salt-sensitive hypertensive rats.
OBJECTIVE We previously showed that the molecule interacting with Ang II type 1 receptor (AT1R), ATRAP, promotes AT1R… Expand
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2010
2010
Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiac hypertrophy in chronic angiotensin II-infused mice.
We cloned a novel molecule interacting with angiotensin II type 1 receptor, which we named ATRAP (for angiotensin II type 1… Expand
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Highly Cited
2007
Highly Cited
2007
A novel class of bacteria-induced small RNAs in Arabidopsis.
Small RNAs, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), are essential regulatory molecules of many cellular… Expand
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2006
2006
Interacting molecule of AT1 receptor, ATRAP, is colocalized with AT1 receptor in the mouse renal tubules.
The renin-angiotensin system in the kidney plays a critical role in the regulation of renal hemodynamics and sodium handling… Expand
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2005
2005
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
Angiotensin II (Ang II) plays a central role in cardiovascular physiology and disease. Ang II type I receptor (AT1) is thought to… Expand
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2002
2002
Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap).
Several classes of cytoplasmic proteins have been found to interact specifically with the carboxyl-terminal cytoplasmic region of… Expand
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2000
2000
ATRAP, novel AT1 receptor associated protein, enhances internalization of AT1 receptor and inhibits vascular smooth muscle cell growth.
We have identified a novel, membrane-located protein that interacts specifically with the carboxyl-terminal cytoplasmic domain of… Expand
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