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AG 1295
Known as:
AG-1295
, AG1295
, Tyrphostin AG 1295
A member of the Tyrphostin family of tyrosine kinase inhibitors that inhibits signal transduction through platelet-derived growth factor receptor and…
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National Institutes of Health
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Related topics
Related topics
1 relation
Receptor Tyrosine Kinase Inhibition
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Bovine lactoferrin stimulates human corneal epithelial alkali wound healing in vitro.
U. Pattamatta
,
M. Willcox
,
F. Stapleton
,
Nerida Cole
,
Q. Garrett
Investigative Ophthalmology and Visual Science
2009
Corpus ID: 2081227
PURPOSE The purpose of this study was to investigate the effect of bovine lactoferrin (BLF) on human corneal epithelial wound…
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Highly Cited
2008
Highly Cited
2008
Differential Behaviors of Atrial Versus Ventricular Fibroblasts: A Potential Role for Platelet-Derived Growth Factor in Atrial-Ventricular Remodeling Differences
B. Burstein
,
E. Libby
,
A. Calderone
,
S. Nattel
Circulation
2008
Corpus ID: 12729883
Background— In various heart disease paradigms, atria show stronger fibrotic responses than ventricles. The possibility that…
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Highly Cited
2006
Highly Cited
2006
UVB-mediated induction of cytokines and growth factors in pterygium epithelial cells involves cell surface receptors and intracellular signaling.
N. Di Girolamo
,
D. Wakefield
,
M. Coroneo
Investigative Ophthalmology and Visual Science
2006
Corpus ID: 14549444
PURPOSE Pterygium is a proliferative, inflammatory, and invasive ocular surface disease associated with excessive ultraviolet (UV…
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Highly Cited
2002
Highly Cited
2002
Src-mediated Inter-receptor Cross-talk between the Na+/K+-ATPase and the Epidermal Growth Factor Receptor Relays the Signal from Ouabain to Mitogen-activated Protein Kinases*
M. Haas
,
Haojie Wang
,
Jiang Tian
,
Zijian Xie
Journal of Biological Chemistry
2002
Corpus ID: 11538018
Binding of ouabain to Na+/K+-ATPase activates tyrosine phosphorylation of the epidermal growth factor receptor (EGFR), Src, and…
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Highly Cited
2002
Highly Cited
2002
Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics.
M. Chorny
,
I. Fishbein
,
H. Danenberg
,
G. Golomb
Journal of Controlled Release
2002
Corpus ID: 22445103
Highly Cited
2001
Highly Cited
2001
A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations.
M. Levis
,
K. Tse
,
B. Smith
,
E. Garrett
,
D. Small
Blood
2001
Corpus ID: 22593698
Internal tandem duplication (ITD) mutations of the receptor tyrosine kinase FLT3 have been found in 20% to 30% of patients with…
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Highly Cited
2001
Highly Cited
2001
Dopamine D(4) and D(2L) Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on trans-Activation of the Platelet-Derived Growth Factor Receptor.
J. Oak
,
N. Lavine
,
H. V. Tol
Molecular Pharmacology
2001
Corpus ID: 14791143
The ability of dopamine D(4) and D(2) receptors to activate extracellular signal-regulated kinases (ERKs) 1 and 2 was compared…
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Highly Cited
2000
Highly Cited
2000
The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation.
T. Mehrens
,
Silke Lelleck
,
+6 authors
E. Schlatter
Journal of the American Society of Nephrology
2000
Corpus ID: 23112702
Members of the organic cation transporter (OCT) family are mainly expressed in kidney, liver, intestine, and brain. The…
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Highly Cited
1998
Highly Cited
1998
PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine.
S. Banai
,
Y. Wolf
,
+11 authors
S. Gertz
Circulation
1998
Corpus ID: 804348
BACKGROUND Signaling through protein tyrosine kinases (PTKs) is a major contributor to the transmission of mitogenic stimuli to…
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Highly Cited
1994
Highly Cited
1994
Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation.
M. Kovalenko
,
A. Gazit
,
+6 authors
A. Levitzki
Cancer Research
1994
Corpus ID: 17546045
A novel class of tyrosine kinase blockers represented by the tyrphostins AG1295 and AG1296 is described. These compounds inhibit…
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