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AG-012986

National Institutes of Health

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2 relations

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BenzamidesThiazoles

Papers overview

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2012
2012
Off‐target immune cell toxicity caused by AG‐012986, a pan‐CDK inhibitor, is associated with inhibition of p38 MAPK phosphorylation
AG‐012986 is a pan‐CDK (cyclin‐dependent kinase) inhibitor that has in vitro and in vivo antitumor properties but was stopped in… 
2008
2008
Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy
AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with… 
2006
2006
Retinal and Peripheral Nerve Toxicity Induced by the Administration of a Pan-Cyclin Dependent Kinase (cdk) Inhibitor in Mice
Cyclin-dependent kinases (cdks) play a crucial role in cell cycle regulation and are considered promising targets for cancer… 
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