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AFN941

 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Staurosporine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Staurosporine scaffold–based rational discovery of the wild‐type sparing reversible inhibitors of EGFR T790M gatekeeper mutant in lung cancer with analog‐sensitive kinase technology
The human epidermal growth factor receptor (EGFR) has been established as an attractive target for lung cancer therapy. However… Expand
2013
2013
Improving EGFR kinase inhibitor design for the targeted treatment of lung cancer.
With over 174,000 new cases of lung cancer being diagnosed in the United States each year novel chemotherapy treatments with… Expand
2007
2007
Therapy: Crystal-clear targets?
ABL http://www.ncbi.nlm.nih.gov/ entrez/query.fcgi?db=gene&c md=Retrieve&dopt=full_ report&list_uids=25 The identification of… Expand
2007
2007
Anticancer drugs: Crystal-clear targets?
ABL http://www.ncbi.nlm.nih.gov/ entrez/query.fcgi?db=gene&c md=Retrieve&dopt=full_ report&list_uids=25 The identification of… Expand
Highly Cited
2005
Highly Cited
2005
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog.
Jak (Janus kinase) family nonreceptor tyrosine kinases are central mediators of cytokine signaling. The Jak kinases exhibit… Expand
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