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ADX 47273

Known as: ADX-47273, ADX47273 
 
National Institutes of Health

Papers overview

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2017
2017
&NA; Hippocampal synaptic plasticity and learning are regulated by metabotropic glutamate receptors (mGlu) and particularly by… Expand
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2015
2015
RationaleImpaired N-methyl-d-aspartate (NMDA) receptor signalling underlies several psychiatric disorders that express high… Expand
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2012
2012
Metabotropic glutamate-5 receptors (mGluR5), which physically and functionally interact with N-methyl-d-Aspartate (NMDA… Expand
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2011
2011
Positive and negative allosteric modulators (PAMs and NAMs, respectively) of the type 5 metabotropic glutamate (mGlu5) receptor… Expand
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2011
2011
This Letter describes a chemical lead optimization campaign directed at a weak mGlu(5) NAM discovered while developing SAR for… Expand
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Highly Cited
2010
Highly Cited
2010
Metabotropic glutamate receptors of the subtype 5 (mGluR(5)) are located in brain regions implicated in schizophrenia such as the… Expand
2009
2009
Recently, it has been proposed that activation of either metabotropic glutamate receptors e.g. mGlu(5) by positive allosteric… Expand
Highly Cited
2008
Highly Cited
2008
Positive allosteric modulators (PAMs) of metabotropic glutamate receptor subtype 5 (mGlu5) enhance N-methyl-d-aspartate receptor… Expand
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2005
2005
Adrenodoxin (Adx), a [2Fe-2S] vertebrate-type ferredoxin, transfers electrons from the NADPH-dependent flavoprotein Adx reductase… Expand
Highly Cited
2001
Highly Cited
2001
To reveal direct effects of androgens, independent of glucocorticoids, we studied the effects of gonadectomy (GDX) in… Expand