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ADP/ATP translocase activity

Known as: adenine nucleotide translocase, ATP/ADP exchanger, ATP:ADP antiporter activity 
Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out). [TC:2.A.29.1.1]
National Institutes of Health

Related topics

Related topics

1 relation
Adenine Nucleotide Translocase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphonates
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of diseases with excess… 
Highly Cited
2005
Highly Cited
2005
The basal proton conductance of mitochondria depends on adenine nucleotide translocase content.
The basal proton conductance of mitochondria causes mild uncoupling and may be an important contributor to metabolic rate. The… 
Highly Cited
2004
Highly Cited
2004
Effects of acute and chronic endurance exercise on mitochondrial uncoupling in human skeletal muscle
Mitochondrial proteins such as uncoupling protein 3 (UCP3) and adenine nucleotide translocase (ANT) may mediate back‐leakage of… 
Highly Cited
2002
Highly Cited
2002
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
Accumulating evidence suggests that mitochondrial membrane permeabilization (MMP) is a rate-limiting step of programmed… 
Highly Cited
2001
Highly Cited
2001
Cardioprotection by ischemic preconditioning preserves mitochondrial function and functional coupling between adenine nucleotide translocase and creatine kinase.
M. N. Laclau, S. Boudina, J. B. Thambo, L. Tariosse, G. Gouverneur, S. Bonoron-Adèle, V. A. Saks, K. D. Garlid and P. Dos Santos… 
Highly Cited
1997
Highly Cited
1997
Tissue‐specific transcription pattern of the adenine nucleotide translocase isoforms in humans
Review
1989
Review
1989
The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism.
Highly Cited
1980
Highly Cited
1980
Postnatal development of rat liver mitochondria: state 3 respiration, adenine nucleotide translocase activity, and the net accumulation of adenine nucleotides.
Highly Cited
1978
Highly Cited
1978
Protection of the ischemic dog myocardium with carnitine.
Highly Cited
1971
Highly Cited
1971
The inhibition of adenine nucleotide translocase activity by oleoyl CoA and its reversal in rat liver mitochondria.
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