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ADAMTS3 gene
Known as:
ADAMTS3
, ADAM metallopeptidase with thrombospondin type 1 motif 3
, ADAMTS-4
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases.
So-Young Lee
,
Hyangsin Lee
,
+4 authors
Chan-Sik Park
Archives of Pathology & Laboratory Medicine
2014
Corpus ID: 30385596
CONTEXT The ability of intermediate trophoblasts to invade maternal tissue during placentation depends on how well they can…
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2014
2014
ADAMTS-4 and Biglycan are Expressed at High Levels and Co-Localize to Podosomes During Endothelial Cell Tubulogenesis In Vitro
M. Obika
,
R. Vernon
,
M. D. Gooden
,
K. Braun
,
Christina K. Chan
,
T. Wight
Journal of Histochemistry and Cytochemistry
2014
Corpus ID: 207356252
Proteolysis of the extracellular matrix influences vascular growth. We examined the expression of ADAMTS-1, -4, and -5…
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2011
2011
Discovery of (1S,2R,3R)-2,3-dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: novel and highly selective aggrecanase inhibitors.
Makoto Shiozaki
,
K. Maeda
,
+22 authors
T. Inaba
Journal of Medicinal Chemistry
2011
Corpus ID: 19120499
Aggrecanases, particularly aggrecanase-1 (ADAMTS-4) and aggrecanase-2 (ADAMTS-5), are believed to be key enzymes involved in the…
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2011
2011
Treatment with Tiludronic Acid Helps Reduce the Development of Experimental Osteoarthritis Lesions in Dogs with Anterior Cruciate Ligament Transection Followed by Reconstructive Surgery: A 1-Year…
J. Pelletier
,
E. Troncy
,
+9 authors
J. Martel-Pelletier
Journal of Rheumatology
2011
Corpus ID: 2462035
Objective. To investigate over a 1-year period in dogs that underwent extracapsular stabilization surgery (ECS) following…
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2010
2010
Design, Synthesis, and Preliminary Biological Evaluation of Pyrrolo[3,4‐c]quinolin‐1‐one and Oxoisoindoline Derivatives as Aggrecanase Inhibitors
A. Cappelli
,
C. Nannicini
,
+9 authors
S. Vomero
ChemMedChem
2010
Corpus ID: 27590698
A small set of aggrecanase inhibitors based on the pyrrolo[3,4‐c]quinolin‐1‐one or oxoisoindoline frameworks bearing a 4…
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Review
2008
Review
2008
Will the real aggrecanase(s) step up: evaluating the criteria that define aggrecanase activity in osteoarthritis.
M. Tortorella
,
A. Malfait
Current Pharmaceutical Biotechnology
2008
Corpus ID: 41535106
Loss of aggrecan from articular cartilage is an early and critical event in the pathogenesis of osteoarthritis (OA) and is…
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2008
2008
Therapeutic effect of Siegesbeckia pubescens on cartilage protection in a rabbit collagenase-induced model of osteoarthritis.
J. Huh
,
Y. Baek
,
Jae-Dong Lee
,
D. Choi
,
Dong-suk Park
Journal of Pharmacological Sciences
2008
Corpus ID: 39981651
Siegesbeckia pubescens (S. pubescens) was widely used to alleviate symptoms of osteoarthritis (OA) in traditional medicine…
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2007
2007
Substrate Conformation Modulates Aggrecanase (ADAMTS-4) Affinity and Sequence Specificity
Janelle L. Lauer-Fields
,
D. Minond
,
T. Sritharan
,
M. Kashiwagi
,
H. Nagase
,
G. Fields
Journal of Biological Chemistry
2007
Corpus ID: 29021030
Protease-substrate interactions are governed by a variety of structural features. Although the substrate sequence specificities…
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2007
2007
Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1).
A. Wittwer
,
Robert L. Hills
,
+5 authors
M. Tortorella
Biochemistry
2007
Corpus ID: 23924270
ADAMTS-4 (aggrecanase-1) is implicated in the breakdown of articular cartilage and is an attractive target for therapeutic…
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2006
2006
Effects of covalently attached chondroitin sulfate on aggrecan cleavage by ADAMTS-4 and MMP-13.
H. E. Miwa
,
T. Gerken
,
T. Hering
Matrix Biology
2006
Corpus ID: 42088420
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