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ADAMTS13 wt Allele

Known as: ADAMTS-13, DKFZp434C2322, A Disintegrin-Like and Metalloprotease With Thrombospondin Type 1 Motif, 13 Gene 
Human ADAMTS13 wild-type allele is located in the vicinity of 9q34 and is approximately 45 kb in length. This allele, which encodes a disintegrin and… 
National Institutes of Health

Related topics

Related topics

5 relations
9q34Blood coagulationHydrolysisIntegrin Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
siRNA-knockdown of ADAMTS-13 modulates endothelial cell angiogenesis.
2016
2016
Evaluation of von Willebrand factor and ADAMTS-13 antigen and activity levels in sickle cell disease patients in Kuwait
Sickle cell disease (SCD) is a severe form of hemolytic anemia characterized by chronic hemolysis and is associated with… 
2012
2012
ADAMTS-13 is produced by glial cells and upregulated after spinal cord injury
2012
2012
Gender-dependent up-regulation of ADAMTS-13 in mice with obesity and hypercholesterolemia.
2011
2011
IL-1β Down-Regulates ADAMTS-13 mRNA Expression in Cells of the Central Nervous System
ADAMTS-13 is the Von Willebrand factor (vWF) cleaving protease, responsible for the cleavage and down-regulation of the pro… 
2011
2011
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting.
Hemiscorpius lepturus is a lethal scorpion with potentially cytotoxic venom. Various degrees of local and systemic toxicity have… 
2009
2009
von Willebrand factor is a major determinant of ADAMTS‐13 decrease during mouse sepsis induced by cecum ligation and puncture
Summary.  Background: During sepsis, von Willebrand factor (VWF) is abundantly secreted; the main mechanism regulating its size… 
2008
2008
ADAMTS-13 activity in the presence of elevated von Willebrand factor levels as a novel mechanism of residual platelet reactivity in high risk coronary patients on antiplatelet treatment.
2006
2006
ADAMTS-13 levels in fresh, stored, and solvent detergent treated plasma.
2006
2006
ADAMTS-13 regulates platelet adhesion under flow
Summary ADAMTS-13 cleaves large and ultra-large vonWillebrand factor multimers normally secreted by endothelial cells. Severe… 
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