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ADAMTS13 wt Allele

Known as: ADAMTS-13, DKFZp434C2322, A Disintegrin-Like and Metalloprotease With Thrombospondin Type 1 Motif, 13 Gene 
Human ADAMTS13 wild-type allele is located in the vicinity of 9q34 and is approximately 45 kb in length. This allele, which encodes a disintegrin and… 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Safety, tolerability, and pharmacokinetics of recombinant ADAMTS-13 (a disintegrin and metalloproteinase with a thrombospondin… 
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Highly Cited
2012
Highly Cited
2012
Background Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with… 
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Highly Cited
2008
Highly Cited
2008
Summary.  Background: Thrombotic thrombocytopenic purpura (TTP) is most commonly associated with deficiency or inhibition of von… 
Highly Cited
2007
Highly Cited
2007
Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma exchange (PEX) remains the primary treatment… 
Highly Cited
2007
Highly Cited
2007
Objective:The inability to regulate the inflammatory response initiated upon infection leads to severe sepsis, characterized by… 
Highly Cited
2006
Highly Cited
2006
Summary.  Hepatic stellate cells have been considered to be a primary source for human plasma ADAMTS‐13, the von Willebrand… 
Highly Cited
2006
Highly Cited
2006
Summary.  Background: Thrombotic thrombocytopenic purpura (TTP), a life‐threatening thrombotic microangiopathy, requires… 
Highly Cited
2004
Highly Cited
2004
The congenital or acquired deficiency of the von Willebrand factor (VWF) cleaving protease, ADAMTS‐13 has been specifically… 
Highly Cited
2003
Highly Cited
2003
Acquired thrombotic thrombocytopenic purpura (TTP) has been linked to severe deficiency of ADAMTS-13 activity caused by… 
Highly Cited
2003
Highly Cited
2003
Summary.  A severely deficient ADAMTS‐13 activity (<5%) is a key laboratory finding confirming the diagnosis of thrombotic…