Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,023,883 papers from all fields of science
Search
Sign In
Create Free Account
ADAMTS13 wt Allele
Known as:
ADAMTS-13
, DKFZp434C2322
, A Disintegrin-Like and Metalloprotease With Thrombospondin Type 1 Motif, 13 Gene
Expand
Human ADAMTS13 wild-type allele is located in the vicinity of 9q34 and is approximately 45 kb in length. This allele, which encodes a disintegrin and…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
5 relations
9q34
Blood coagulation
Hydrolysis
Integrin Binding
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Recombinant ADAMTS-13: first-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura.
M. Scully
,
P. Knöbl
,
+11 authors
B. Ewenstein
Blood
2017
Corpus ID: 22692129
Safety, tolerability, and pharmacokinetics of recombinant ADAMTS-13 (a disintegrin and metalloproteinase with a thrombospondin…
Expand
Highly Cited
2012
Highly Cited
2012
Severe Dengue Is Associated with Consumption of von Willebrand Factor and Its Cleaving Enzyme ADAMTS-13
K. Djamiatun
,
A. J. van der Ven
,
+6 authors
Q. de Mast
PLoS Neglected Tropical Diseases
2012
Corpus ID: 1270882
Background Thrombocytopenia, bleeding and plasma leakage are cardinal features of severe dengue. Endothelial cell activation with…
Expand
Highly Cited
2008
Highly Cited
2008
Prevalence of the ADAMTS‐13 missense mutation R1060W in late onset adult thrombotic thrombocytopenic purpura
R. Camilleri
,
H. Cohen
,
+5 authors
S. Machin
Journal of Thrombosis and Haemostasis
2008
Corpus ID: 25660231
Summary. Background: Thrombotic thrombocytopenic purpura (TTP) is most commonly associated with deficiency or inhibition of von…
Expand
Highly Cited
2007
Highly Cited
2007
Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS‐13
M. Scully
,
H. Cohen
,
+5 authors
S. Machin
British Journal of Haematology
2007
Corpus ID: 24870209
Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma exchange (PEX) remains the primary treatment…
Expand
Highly Cited
2007
Highly Cited
2007
Decreased ADAMTS-13 (A disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure*
K. Martin
,
D. Borgel
,
+7 authors
D. Baruch
Critical Care Medicine
2007
Corpus ID: 41225058
Objective:The inability to regulate the inflammatory response initiated upon infection leads to severe sepsis, characterized by…
Expand
Highly Cited
2006
Highly Cited
2006
Human endothelial cells synthesize and release ADAMTS‐13
N. Turner
,
L. Nolasco
,
Z. Tao
,
J. Dong
,
J. Moake
Journal of Thrombosis and Haemostasis
2006
Corpus ID: 36843847
Summary. Hepatic stellate cells have been considered to be a primary source for human plasma ADAMTS‐13, the von Willebrand…
Expand
Highly Cited
2004
Highly Cited
2004
von Willebrand factor cleaving protease (ADAMTS‐13) and ADAMTS‐13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura
F. Peyvandi
,
S. Ferrari
,
S. Lavoretano
,
M. Canciani
,
P. Mannucci
British Journal of Haematology
2004
Corpus ID: 7625918
The congenital or acquired deficiency of the von Willebrand factor (VWF) cleaving protease, ADAMTS‐13 has been specifically…
Expand
Highly Cited
2004
Highly Cited
2004
Splenectomy in relapsing and plasma-refractory acquired thrombotic thrombocytopenic purpura.
J. K. Kremer Hovinga
,
J. Studt
,
+7 authors
B. Lämmle
Haematologica
2004
Corpus ID: 34997780
BACKGROUND AND OBJECTIVES Acquired thrombotic thrombocytopenic purpura (TTP) is often due to autoantibodies inhibiting ADAMTS-13…
Expand
Highly Cited
2003
Highly Cited
2003
Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura.
F. Scheiflinger
,
P. Knöbl
,
+5 authors
M. Rieger
Blood
2003
Corpus ID: 26067421
Acquired thrombotic thrombocytopenic purpura (TTP) has been linked to severe deficiency of ADAMTS-13 activity caused by…
Expand
Highly Cited
2003
Highly Cited
2003
Measurement of von Willebrand factor‐cleaving protease (ADAMTS‐13) activity in plasma: a multicenter comparison of different assay methods
J. Studt
,
M. Böhm
,
U. Budde
,
J. Girma
,
K. Váradi
,
B. Lämmle
Journal of Thrombosis and Haemostasis
2003
Corpus ID: 28537050
Summary. A severely deficient ADAMTS‐13 activity (<5%) is a key laboratory finding confirming the diagnosis of thrombotic…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE