Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 224,979,039 papers from all fields of science
Search
Sign In
Create Free Account
ADAM10 Protein
Known as:
Disintegrin and Metalloproteinase Domain-Containing Protein 10
, CD156c Antigen
, ADAM-10 Protein
Expand
A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
9 relations
Narrower (2)
ADAM10 protein, human
Disintegrin and Metalloproteinase Domain-Containing Protein 10, human
In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Regulation des shedding von Membranproteinen durch ADAM10
Kristin Endres
BIOspektrum
2019
Corpus ID: 255553267
2019
2019
Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway
Fei Feng
,
Yuanyuan Li
,
Nanqu Huang
,
Yong Luo
PeerJ
2019
Corpus ID: 209378148
Background Icaritin (ICT) is a prenylflavonoid derivative from Epimedium brevicornum Maxim. ICT has been shown to have…
Expand
2018
2018
Visualization of Alzheimer’s Disease Related α-/β-/γ-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer
Xin Wang
,
G. Pei
Frontiers in Molecular Neuroscience
2018
Corpus ID: 53750492
The competitive ectodomain shedding of amyloid-β precursor protein (APP) by α-secretase and β-secretase, and the subsequent…
Expand
Review
2017
Review
2017
Synaptic dysfunction in Alzheimer's disease: From the role of amyloid β-peptide to the α-secretase ADAM10.
Stefano Musardo
,
E. Marcello
European Journal of Pharmacology
2017
Corpus ID: 207582913
2017
2017
THU0064 ADAM-10 as a tocilizumab treatment predictive factor in rheumatoid arthritis
T. Isozaki
,
S. Nishimi
,
+5 authors
T. Kasama
2017
Corpus ID: 80437332
Background A disintegrin and metalloproteinases (ADAMs) are a family of transmembrane and secreted proteins. ADAM-10 has been…
Expand
2015
2015
The role of the TLR4/NF-κB signaling pathway in Aβ accumulation in primary hippocampal neurons.
Dan Wu
,
Xian Zhang
,
Min Zhao
,
Ai-ling Zhou
Sheng li xue bao : [Acta physiologica Sinica]
2015
Corpus ID: 23486951
The present study aimed to investigate the role of the Toll-like receptor 4 (TLR4)/nuclear factor κB (NF-κB) signaling pathway in…
Expand
2013
2013
Inhibition of Amyloid Precursor Protein Processing Enhances Gemcitabine-mediated Cytotoxicity in Pancreatic Cancer Cells*
N. Woods
,
J. Padmanabhan
Journal of Biological Chemistry
2013
Corpus ID: 205330707
Background: Amyloid precursor protein (APP) and ADAM10, main α-secretase involved in generation of secreted APP (sAPPα), are…
Expand
2012
2012
Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer’s disease mouse model
J. Chu
,
D. Praticò
Journal of Neuroinflammation
2012
Corpus ID: 255959732
The 5-lipoxygenase enzyme is widely distributed within the central nervous system and its activity is regulated by the presence…
Expand
2011
2011
TRAFFICKING OF α-SECRETASE ADAM10: NEW INSIGHTS INTO THE MOLECULAR MECHANISM OF MODULATION
Scienze Farmacologiche
,
Facoltà di Farmacia
,
Scienze Farmacotossicologiche
,
Xxiv Ciclo
2011
Corpus ID: 86194907
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE