Skip to search formSkip to main contentSkip to account menu

ADAM10 Protein

Known as: Disintegrin and Metalloproteinase Domain-Containing Protein 10, CD156c Antigen, ADAM-10 Protein 
A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE… 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (2)

ADAM10 protein, humanDisintegrin and Metalloproteinase Domain-Containing Protein 10, human
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Regulation des shedding von Membranproteinen durch ADAM10
2019
2019
Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway
Background Icaritin (ICT) is a prenylflavonoid derivative from Epimedium brevicornum Maxim. ICT has been shown to have… 
2018
2018
Visualization of Alzheimer’s Disease Related α-/β-/γ-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer
The competitive ectodomain shedding of amyloid-β precursor protein (APP) by α-secretase and β-secretase, and the subsequent… 
Review
2017
Review
2017
Synaptic dysfunction in Alzheimer's disease: From the role of amyloid β-peptide to the α-secretase ADAM10.
2017
2017
THU0064 ADAM-10 as a tocilizumab treatment predictive factor in rheumatoid arthritis
Background A disintegrin and metalloproteinases (ADAMs) are a family of transmembrane and secreted proteins. ADAM-10 has been… 
2015
2015
The role of the TLR4/NF-κB signaling pathway in Aβ accumulation in primary hippocampal neurons.
The present study aimed to investigate the role of the Toll-like receptor 4 (TLR4)/nuclear factor κB (NF-κB) signaling pathway in… 
2013
2013
Inhibition of Amyloid Precursor Protein Processing Enhances Gemcitabine-mediated Cytotoxicity in Pancreatic Cancer Cells*
Background: Amyloid precursor protein (APP) and ADAM10, main α-secretase involved in generation of secreted APP (sAPPα), are… 
2012
2012
Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer’s disease mouse model
The 5-lipoxygenase enzyme is widely distributed within the central nervous system and its activity is regulated by the presence… 
2011
2011
TRAFFICKING OF α-SECRETASE ADAM10: NEW INSIGHTS INTO THE MOLECULAR MECHANISM OF MODULATION
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)