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ACVR1 wt Allele

Known as: FOP, Activin A Receptor, Type I Gene, ACTRI 
Human ACVR1 wild-type allele is located within 2q23-q24 and is approximately 139 kb in length. This allele, which encodes activin receptor type-1… 
National Institutes of Health

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10 relations
2q23-q24ACVR1 geneACVR1 protein, humanFibrodysplasia Ossificans Progressiva

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Mechanisms of neuroprotection against ischemic insult by stress‐inducible phosphoprotein‐1/prion protein complex
Stress‐inducible phosphoprotein 1 (STI1) acts as a neuroprotective factor in the ischemic brain and its levels are increased… 
2017
2017
A new form of IRIDA due to combined heterozygous mutations of TMPRSS6 and ACVR1A encoding the BMP receptor ALK2.
To the editor: The liver expression of the key iron regulator hepcidin is controlled by the bone morphogenetic protein (BMP… 
2015
2015
Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells
The significant role of the embryonic morphogen Nodal in maintaining the pluripotency of embryonic stem cells is well documented… 
2015
2015
ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease
Hepcidin, a key liver peptide hormone, is essential to the regulation of bioavailable iron and erythropoiesis. Activin-like… 
2006
2006
Differential expression of mRNAs encoding the putative inhibin co-receptor (betaglycan) and activin type-I and type-II receptors in preovulatory and prehierarchical follicles of the laying hen ovary.
Ovarian follicle development is primarily regulated by an interplay between the pituitary gonadotrophins, LH and FSH, and ovary… 
2005
2005
n-Alkane and clofibrate, a peroxisome proliferator, activate transcription of ALK2 gene encoding cytochrome P450alk2 through distinct cis-acting promoter elements in Candida maltosa.
1998
1998
The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells.
1997
1997
Ovarian activin receptor subtype and follistatin gene expression in rats: reciprocal regulation by gonadotropins.
The production of activin, follistatin (FS), and inhibin, proteins present in the ovary and involved in mammalian reproduction… 
1994
1994
Ovarian regulation of pituitary inhibin subunit and activin receptor type II gene expression: evidence for a nonsteroidal inhibitory substance.
Gonadotropin subunit gene expression is regulated by gonadal, hypothalamic, and locally derived hormones. In particular, activin… 
Highly Cited
1993
Highly Cited
1993
A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic factor.
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