ACVR1 gene

Known as: Activin A Receptor, Type I Gene, ACTIVIN RECEPTOR-LIKE KINASE 2, ACTIVIN A RECEPTOR, TYPE II-LIKE KINASE 2 
This gene plays a role in the transforming growth factor-beta signal transduction pathway through serine/threonine specificity.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor… (More)
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Highly Cited
2014
Highly Cited
2014
Diffuse intrinsic pontine glioma (DIPG) is a fatal brain cancer that arises in the brainstem of children, with no effective… (More)
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Highly Cited
2009
Highly Cited
2009
Fibrodysplasia ossificans progressiva (FOP) is an autosomal dominant human disorder of bone formation that causes developmental… (More)
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Highly Cited
2009
Highly Cited
2009
Patients with classic fibrodysplasia ossificans progressiva, a disorder characterized by extensive extraskeletal endochondral… (More)
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Highly Cited
2008
Highly Cited
2008
We report engineering Thermoanaerobacterium saccharolyticum, a thermophilic anaerobic bacterium that ferments xylan and biomass… (More)
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Highly Cited
2006
Highly Cited
2006
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder of skeletal malformations and progressive… (More)
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Highly Cited
2005
Highly Cited
2005
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor (TGF)beta superfamily of ligands that regulate… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Juvenile polyposis (JP) is an autosomal dominant syndrome predisposing to colorectal and gastric cancer. We have… (More)
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Highly Cited
2004
Highly Cited
2004
Clinically, there is a great need for small molecule inhibitors that could control pathogenic effects of transforming growth… (More)
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Highly Cited
2002
Highly Cited
2002
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… (More)
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