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ACTIVATED PI3K-DELTA SYNDROME

Known as: PASLI, APDS, p110-DELTA-ACTIVATING MUTATION CAUSING SENESCENT T CELLS, LYMPHADENOPATHY, AND IMMUNODEFICIENCY 
National Institutes of Health

Related topics

Related topics

8 relations
Autosomal dominant inheritanceBronchiectasisCellulitisHypogammaglobulinemia

Broader (2)

Class I Phosphatidylinositol 3-KinasesImmunologic Deficiency Syndromes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The Treatment of Activated PI3Kδ Syndrome
Activated phosphoinositide 3-kinase δ syndrome (APDS), also known as PASLI disease (p110d-activating mutation causing senescent T… 
Review
2018
Review
2018
Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome
The activated phosphoinositide 3-kinase δ syndrome (APDS), also known as p110δ-activating mutation causing senescent T cells… 
Highly Cited
2017
Highly Cited
2017
Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.
The predominant expression of phosphoinositide 3-kinase δ (PI3Kδ) in leukocytes and its critical role in B and T cell functions… 
Review
2016
Review
2016
Genomics of Immune Diseases and New Therapies.
Genomic DNA sequencing technologies have been one of the great advances of the 21st century, having decreased in cost by seven… 
2011
2011
InGaAs-InP avalanche photodiodes with dark current limited by generation-recombination.
Separate absorption grading charge multiplication avalanche photodiodes (SAGCM APDs) are widely accepted in photon starved… 
2006
2006
The N‐terminus of phosphoinositide 3‐kinase‐C2β regulates lipid kinase activity and binding to clathrin
The class II phosphoinositide 3‐kinase (PI3K)‐C2β is recruited to polypeptide growth factor receptors following ligand… 
Highly Cited
2005
Highly Cited
2005
Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
The lipid products of phosphoinositide 3-kinase (PI3K) are involved in many cellular responses such as proliferation, migration… 
2003
2003
Nuclear phosphoinositide 3-kinase C2beta activation during G2/M phase of the cell cycle in HL-60 cells.
Highly Cited
2001
Highly Cited
2001
Presence and Activation of Nuclear Phosphoinositide 3-Kinase C2β during Compensatory Liver Growth*
Highly purified liver nuclei incorporated radiolabeled phosphate into phosphatidylinositol 4-phosphate (PtdIns(4)P), PtdIns(4,5… 
Highly Cited
2001
Highly Cited
2001
Recruitment of the Class II Phosphoinositide 3-Kinase C2β to the Epidermal Growth Factor Receptor: Role of Grb2
ABSTRACT Previously we demonstrated that the class II phosphoinositide 3-kinase C2β (PI3K-C2β) is rapidly recruited to a… 
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