ACTA2 gene

Known as: ACTIN, ALPHA-2, SMOOTH MUSCLE, AORTA, ACTA2, Actin, Alpha 2, Smooth Muscle, Aorta Gene 
This gene plays a role in both cell morphology and cell motility.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Thoracic aortic aneurysm/dissection (TAAD) is a common phenotype that may occur as an isolated manifestation or within… (More)
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2013
2013
Smooth muscle α actin (Acta2) expression is largely restricted to smooth muscle cells, pericytes and specialized fibroblasts… (More)
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2013
2013
PURPOSE Metastatic relapse of primary lung cancer leads to therapeutic resistance and unfavorable clinical prognosis; therefore… (More)
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2012
2012
Mutations in the ACTA2 gene lead to diffuse and diverse vascular diseases; the Arg179His mutation is associated with an early… (More)
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2011
2011
Mutations in the gene encoding smooth muscle cell alpha actin (ACTA2) have recently been shown to cause familial thoracic aortic… (More)
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2011
2011
OBJECTIVE To evaluate the prevalence and phenotype of smooth muscle alpha-actin (ACTA2) mutations in non-syndromic thoracic… (More)
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2011
2011
The discovery of common genetic patterns in different system vascular diseases may provide important insights into the… (More)
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Highly Cited
2010
Highly Cited
2010
Smooth muscle cells (SMCs) contract to perform many physiological functions, including regulation of blood flow and pressure in… (More)
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Highly Cited
2009
Highly Cited
2009
The vascular smooth muscle cell (SMC)-specific isoform of alpha-actin (ACTA2) is a major component of the contractile apparatus… (More)
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2009
2009
Approximately 20% of aortic aneurysm and/or dissection (AAD) cases result from inherited disorders, including several systemic… (More)
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