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ACO1 gene

Known as: IRON-RESPONSIVE ELEMENT-BINDING PROTEIN 1, ACO1, IRON REGULATORY PROTEIN 1 
 
National Institutes of Health

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Related topics

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Iron Regulatory Protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Iron regulatory proteins (Irps) 1 and 2 posttranscriptionally control the expression of transcripts that contain iron-responsive… Expand
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Highly Cited
2010
Highly Cited
2010
Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1*♦
Iron influx increases the translation of the Alzheimer amyloid precursor protein (APP) via an iron-responsive element (IRE) RNA… Expand
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Review
2006
Review
2006
The role of iron regulatory proteins in mammalian iron homeostasis and disease
  • T. Rouault
  • Nature chemical biology
  • 2006
    • Corpus ID: 4231191
Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are mammalian proteins that register cytosolic iron concentrations and post… Expand
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Highly Cited
2006
Highly Cited
2006
Crystal structure of human iron regulatory protein 1 as cytosolic aconitase.
Iron regulatory proteins (IRPs) control the translation of proteins involved in iron uptake, storage and utilization by binding… Expand
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Review
2004
Review
2004
Iron Metabolism and the IRE/IRP Regulatory System: An Update
  • K. Pantopoulos
  • Annals of the New York Academy of Sciences
  • 2004
    • Corpus ID: 28147509
Abstract: Cellular iron homeostasis is accomplished by the coordinated regulated expression of the transferrin receptor and… Expand
Highly Cited
2004
Highly Cited
2004
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
The two iron regulatory proteins IRP1 and IRP2 bind to transcripts of ferritin, transferrin receptor and other target genes to… Expand
Highly Cited
2000
Highly Cited
2000
Alterations in the interaction between iron regulatory proteins and their iron responsive element in normal and Alzheimer's diseased brains.
Iron regulatory proteins (IRPs) are cytoplasmic mRNA binding proteins involved in intracellular regulation of iron homeostasis… Expand
Highly Cited
1999
Highly Cited
1999
Hypoxia Post-translationally Activates Iron-regulatory Protein 2*
Iron-regulatory proteins 1 and 2 (IRP1 and IRP2) are RNA-binding proteins that post-transcriptionally regulate the expression of… Expand
Highly Cited
1998
Highly Cited
1998
The yersiniabactin biosynthetic gene cluster of Yersinia enterocolitica: organization and siderophore-dependent regulation.
The ability to synthesize and uptake the Yersinia siderophore yersiniabactin is a hallmark of the highly pathogenic, mouse-lethal… Expand
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Highly Cited
1995
Highly Cited
1995
Requirements for iron‐regulated degradation of the RNA binding protein, iron regulatory protein 2.
Iron regulatory proteins (IRPs) regulate the expression of genes involved in iron metabolism whose transcripts contain RNA stem… Expand
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