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ABT 719

Known as: ABT-719, ABT719 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
ABSTRACT Introduction: Despite significant need and historical trials, there are no effective drugs in use for the prevention or… Expand
2016
2016
Background Patients undergoing cardiac surgeries with cardiopulmonary bypass (on‐pump) have a high risk for acute kidney injury… Expand
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Highly Cited
1999
Highly Cited
1999
  • Z. Ma, D. Chu, +9 authors Y. Or
  • Journal of medicinal chemistry
  • 1999
  • Corpus ID: 25441516
The antibacterial 4H-4-oxoquinolizines were introduced recently to overcome bacterial resistance to fluoroquinolones. They… Expand
Highly Cited
1996
Highly Cited
1996
Two novel series of 2-pyridones were synthesized by transposition of the nitrogen of 4-quinolones to the bridgehead position… Expand
1996
1996
ABT-719 is a 2-pyridone antimicrobial which inhibits DNA gyrase activity. It has considerable subcutaneous (sc) and oral efficacy… Expand
1995
1995
ABT-719 (A-86719.1) is the first compound of a new class of novel DNA gyrase inhibitors, the 2-pyridones, with potent… Expand
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1995
1995
The 2-pyridones are a new class of broad-spectrum orally bioavailable antibacterial agents. These compounds are potent bacterial… Expand
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