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ABT 719

Known as: ABT-719, ABT719 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
INTRODUCTION Despite significant need and historical trials, there are no effective drugs in use for the prevention or treatment… Expand
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2016
2016
BACKGROUND Patients undergoing cardiac surgeries with cardiopulmonary bypass (on-pump) have a high risk for acute kidney injury… Expand
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1999
1999
The antibacterial 4H-4-oxoquinolizines were introduced recently to overcome bacterial resistance to fluoroquinolones. They… Expand
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1996
1996
ABT-719 is a 2-pyridone antimicrobial which inhibits DNA gyrase activity. It has considerable subcutaneous (sc) and oral efficacy… Expand
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1996
1996
Two novel series of 2-pyridones were synthesized by transposition of the nitrogen of 4-quinolones to the bridgehead position… Expand
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1995
1995
ABT-719 (A-86719.1) is the first compound of a new class of novel DNA gyrase inhibitors, the 2-pyridones, with potent… Expand
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1995
1995
The 2-pyridones are a new class of broad-spectrum orally bioavailable antibacterial agents. These compounds are potent bacterial… Expand
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