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ABT 719

Known as: ABT-719, ABT719 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyridones

Papers overview

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Review
2017
Review
2017
Recent early clinical drug development for acute kidney injury
ABSTRACT Introduction: Despite significant need and historical trials, there are no effective drugs in use for the prevention or… 
2016
2016
ABT‐719 for the Prevention of Acute Kidney Injury in Patients Undergoing High‐Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial
Background Patients undergoing cardiac surgeries with cardiopulmonary bypass (on‐pump) have a high risk for acute kidney injury… 
Highly Cited
1999
Highly Cited
1999
Synthesis and antimicrobial activity of 4H-4-oxoquinolizine derivatives: consequences of structural modification at the C-8 position.
  • Z. MaD. Chu Y. Or
  • Journal of Medicinal Chemistry
  • 1999
  • Corpus ID: 25441516
The antibacterial 4H-4-oxoquinolizines were introduced recently to overcome bacterial resistance to fluoroquinolones. They… 
1996
1996
Efficacy of ABT-719, a 2-pyridone antimicrobial, against enterococci, Escherichia coli, and Pseudomonas aeruginosa in experimental murine pyelonephritis.
ABT-719 is a 2-pyridone antimicrobial which inhibits DNA gyrase activity. It has considerable subcutaneous (sc) and oral efficacy… 
1995
1995
In vitro evaluation of ABT-719, a novel DNA gyrase inhibitor
ABT-719 (A-86719.1) is the first compound of a new class of novel DNA gyrase inhibitors, the 2-pyridones, with potent… 
1995
1995
Efficacies of ABT-719 and related 2-pyridones, members of a new class of antibacterial agents, against experimental bacterial infections
The 2-pyridones are a new class of broad-spectrum orally bioavailable antibacterial agents. These compounds are potent bacterial… 
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