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ABT 239

Known as: ABT-239, ABT239 
 
National Institutes of Health

Papers overview

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2016
2016
Histaminergic H3 receptors (H3R) antagonists enhance cognition in preclinical models and modulate neurotransmission, in… Expand
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2014
2014
The multifaceted pathogenesis of temporal lobe epilepsy (TLE) offers a number of adjunctive therapeutic prospects. One such… Expand
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2013
2013
Histamine axons originate solely from the tuberomamillary nucleus (TMN) to innervate almost all brain regions. This feature is… Expand
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Highly Cited
2011
Highly Cited
2011
Histamine H(3) receptor antagonists enhance cognition in preclinical models and have been proposed as novel therapeutics for… Expand
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Highly Cited
2010
Highly Cited
2010
Prenatal ethanol exposure causes deficits in hippocampal synaptic plasticity and learning. At present, there are no clinically… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Drinking during pregnancy has been associated with learning disabilities in affected offspring. At present, there are… Expand
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Highly Cited
2005
Highly Cited
2005
Acute pharmacological blockade of central histamine H3 receptors (H3Rs) enhances arousal/attention in rodents. However, there is… Expand
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Highly Cited
2005
Highly Cited
2005
Histamine H3 receptor antagonists are being developed to treat a variety of neurological and cognitive disorders that may be… Expand
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Highly Cited
2005
Highly Cited
2005
H(3) receptor antagonists based on a 2-aminoethylbenzofuran skeleton have been discovered, which are potent in vitro at human and… Expand
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2005
2005
Since H3 receptor (H3R) antagonists/inverse agonists can improve cognitive function in animal models, they may have the potential… Expand
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