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ABT 229

Known as: ABT-229 
National Institutes of Health

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Alemcinal

Papers overview

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2010
2010
[Effect of interstitial cells of Cajal on gastrointestinal motility induced by motilin receptor agonist ABT-229].
OBJECTIVE To investigate the effect of interstitial cells of Cajal (ICC) on contraction of intestinal tract smooth muscle induced… 
2008
2008
Differences in motilin receptor desensitization after stimulation with motilin or motilides are due to alternative receptor trafficking.
2006
2006
The GERD market
Gastroesophageal reflux disease (GERD) occurs when stomach contents flow into the esophagus. GERD sufferers often complain of a… 
2002
2002
Efficacy of a motilin receptor agonist (ABT‐229) for the treatment of gastro‐oesophageal reflux disease
ABT‐229 is a potent motilin agonist without significant antibiotic activity. It has been shown to improve gastric emptying in… 
2001
2001
Demonstration of a functional motilin receptor in TE671 cells from human cerebellum
2001
2001
ects of a motilin receptor agonist ( ABT-229 ) on upper gastrointestinal symptoms in type 1 diabetes mellitus : a randomised , double blind , placebo controlled trial
Introduction—Erythromycin, a motilin agonist, is a potent prokinetic. ABT-229 is a specific motilin agonist that dose dependently… 
2000
2000
Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin.
We investigated the in vivo and in vitro locus of actions of prokinetics: motilin, erythromycin, and ABT-229. The test substances… 
1999
1999
AN ACTION OF ERYTHROMYCIN IN THE INTESTINE THAT IS NOT MEDIATED VIA MOTILIN RECEPTORS
1. Erythromycin lactobionate caused a concentration‐ dependent inhibition of nerve‐mediated contractions of the longitudinal… 
1998
1998
Synthesis of 9-deoxo-4''-deoxy-6,9-epoxyerythromycin derivatives: novel and acid-stable motilides.
In our quest toward the discovery of highly potent and acid-stable motilides, novel 4"-deoxy derivatives of 9-deoxo-6, 9… 
1996
1996
The safety and pharmacodynamics of a single dose of a new prokinetic macrolide (ABT-229) in healthy adult subjects
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