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ABT 107

Known as: ABT-107, ABT107 
National Institutes of Health

Papers overview

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2015
2015
α7 nicotinic receptor agonists reduce levodopa‐induced dyskinesias with severe nigrostriatal damage
ABT‐126 is a novel, safe, and well‐tolerated α7 nicotinic receptor agonist in a Phase 2 Alzheimer's disease study. We tested the… 
2015
2015
ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice
Nicotine withdrawal produces cognitive deficits that can predict relapse. Amelioration of these cognitive deficits emerges as a… 
2015
2015
Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia.
2015
2015
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
2014
2014
The α7 Nicotinic Receptor Agonist ABT-107 Decreases l-Dopa–Induced Dyskinesias in Parkinsonian Monkeys
Previous studies in Parkinsonian rats and monkeys have shown that β2-selective nicotinic acetylcholine receptor (nAChR) agonists… 
2014
2014
Effects of systemically applied nAChRα7 agonists and antagonists on light-induced phase shifts of hamster circadian activity rhythms
2014
2014
Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats
2013
2013
Species-dependent metabolism of a novel selective α7 neuronal acetylcholine receptor agonist ABT-107
Abstract 1. Metabolism of ABT-107 was investigated in in vitro hepatic systems, in rat and monkey receiving [14C]ABT-107, and in… 
2011
2011
Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis
Antipsychotics normalize responses in the DBA/2 mouse model of prepulse inhibition (PPI), a preclinical model of sensorimotor… 
Highly Cited
2010
Highly Cited
2010
In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107
Enhancement of α7 nicotinic acetylcholine receptor (nAChR) activity is considered a therapeutic approach for ameliorating… 
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