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ABT 102

Known as: ABT-102, ABT102 
 
National Institutes of Health

Papers overview

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2016
2016
Amorphous nanoparticles are able to enhance the kinetic solubility and concomitant dissolution rates of BCS class II and BCS… Expand
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2016
2016
Amorphous solid dispersions typically suffer storage stability issues due to: their amorphous nature, high drug loading, uneven… Expand
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2014
2014
Our aim was to explore the influence of micelles and microparticles emerging in aqueous dispersions of amorphous solid… Expand
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Highly Cited
2012
Highly Cited
2012
Amorphous solid dispersions (ASDs) represent a promising formulation approach for poorly soluble drugs. We explored the… Expand
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2012
2012
Amorphous solid dispersions (ASDs) are a promising formulation approach for poorly soluble active pharmaceutical ingredients… Expand
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2012
2012
ABT-102 is a selective TRPV1 antagonist with robust efficacy in several preclinical models of pain. Three phase 1 studies… Expand
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Highly Cited
2011
Highly Cited
2011
The capsaicin receptor (TRPV1) antagonist ABT-102 demonstrates efficacy in multiple preclinical pain models. However, evolving… Expand
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Highly Cited
2009
Highly Cited
2009
Transient receptor potential vanilloid type 1 (TRPV1) is a ligand-gated ion channel that functions as an integrator of multiple… Expand
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2008
2008
Vanilloid receptor TRPV1 is a cation channel that can be activated by a wide range of noxious stimuli, including capsaicin, acid… Expand
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2008
2008
The transient receptor potential vanilloid (TRPV) 1 receptor, a nonselective cation channel expressed on peripheral sensory… Expand
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