ABHD5 gene

Known as: abhydrolase domain containing 5, ABHYDROLASE DOMAIN-CONTAINING 5, CGI58 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
0520042017

Papers overview

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2015
2015
CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under… (More)
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2013
2013
Triglyceride (TG) accumulation in hepatocytes (hepatic steatosis) preludes the development of advanced nonalcoholic fatty liver… (More)
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2012
2012
Adipose triglyceride lipase (ATGL) is rate-limiting for the initial step of triacylglycerol (TAG) hydrolysis, generating… (More)
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2011
2011
Perilipin (PLIN1) is a constitutive adipocyte lipid droplet coat protein. N-terminal amphipathic helices and central hydrophobic… (More)
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2010
2010
Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in… (More)
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2010
2010
Lipid droplets (LDs) are intracellular storage sites for triacylglyerols (TAGs)and steryl esters, and play essential roles in… (More)
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2009
2009
Lipolysis of stored triacylglycerols provides lipid precursors for the assembly of apolipoprotein B (apoB) lipoproteins in… (More)
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Highly Cited
2007
Highly Cited
2007
A lipid droplet (LD)-associated protein, perilipin, is a critical regulator of lipolysis in adipocytes. We previously showed that… (More)
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Highly Cited
2004
Highly Cited
2004
Perilipins, the major structural proteins coating the surfaces of mature lipid droplets of adipocytes, play an important role in… (More)
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Highly Cited
2004
Highly Cited
2004
Lipid droplets (LDs) are a class of ubiquitous cellular organelles that are involved in lipid storage and metabolism. Although… (More)
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