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ABHD6 gene
Known as:
ABHD6
, ABHYDROLASE DOMAIN-CONTAINING PROTEIN 6
, abhydrolase domain containing 6
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National Institutes of Health
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Related topics
Related topics
1 relation
ABHD5 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.
Shakiru O. Alapafuja
,
M. Malamas
,
+10 authors
A. Makriyannis
Bioorganic & Medicinal Chemistry
2019
Corpus ID: 53568570
2019
2019
Pseudomonas aeruginosa esterase PA2949, a bacterial homolog of the human membrane esterase ABHD6: expression, purification and crystallization
Florian Bleffert
,
J. Granzin
,
H. Gohlke
,
R. Batra-Safferling
,
K. Jaeger
,
F. Kovačić
Acta Crystallographica Section F Structural…
2019
Corpus ID: 96436346
Homologous expression of the membrane-bound esterase PA2949 from Pseudomonas aeruginosa PA01 and the purification of detergent…
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2019
2019
Low mRNA expression and activity of monoacylglycerol lipase in human SH-SY5Y neuroblastoma cells.
J. Szeremeta
,
J. Karlsson
,
Mireille Alhouayek
,
C. Fowler
Prostaglandins & other lipid mediators
2019
Corpus ID: 111391114
2018
2018
Gene Expression of ABHD6, a Key Factor in the Endocannabinoid System, Can Be Modulated by Female Hormones in Human Immune Cells
M. N. Drehmer
,
Y. Muniz
,
A. Marrero
,
S. Löfgren
Biochemical Genetics
2018
Corpus ID: 49722978
One of the main risk factors for the development of an autoimmune disease is to be a woman. Much attention has been given to the…
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2015
2015
Optimization of 1,2,5‐Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors
Jayendra Z. Patel
,
T. Nevalainen
,
+15 authors
Teija Parkkari
ChemMedChem
2015
Corpus ID: 5594174
At present, inhibitors of α/β‐hydrolase domain 6 (ABHD6) are viewed as a promising approach to treat inflammation and metabolic…
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2015
2015
Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.
Jayendra Z. Patel
,
J. van Bruchem
,
+6 authors
T. Nevalainen
Bioorganic & Medicinal Chemistry
2015
Corpus ID: 31894635
2014
2014
Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus
L. Parker
,
M. Niphakis
,
+7 authors
B. Cravatt
Psychopharmacology
2014
Corpus ID: 253748845
To determine the role of the endocannabinoid, 2-arachodonyl glycerol (2-AG), in the regulation of nausea and vomiting. We…
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2013
2013
Highly Predictive Ligand‐based Pharmacophore and Homology Models of ABHD6
Anna L. Bowman
,
A. Makriyannis
Chemical Biology and Drug Design
2013
Corpus ID: 41293810
α/β‐Hydrolase domain‐containing 6 (ABHD6) represents a potentially attractive therapeutic target for indirectly potentiating 2…
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Highly Cited
2012
Highly Cited
2012
O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors.
M. Niphakis
,
Douglas S. Johnson
,
T. Ballard
,
C. Stiff
,
B. Cravatt
ACS Chemical Neuroscience
2012
Corpus ID: 38165350
The two major endocannabinoid transmitters, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are degraded by distinct enzymes…
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Highly Cited
2011
Highly Cited
2011
COX‐2 and fatty acid amide hydrolase can regulate the time course of depolarization‐induced suppression of excitation
A. Straiker
,
J. Wager-Miller
,
S.S. Hu
,
JL Blankman
,
B. Cravatt
,
K. Mackie
British Journal of Pharmacology
2011
Corpus ID: 40932106
BACKGROUND AND PURPOSE Depolarization‐induced suppression of inhibition (DSI) and excitation (DSE) are two forms of cannabinoid…
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