ABCC2 gene

Known as: MULTISPECIFIC ORGANIC ANION TRANSPORTER, CANALICULAR, ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Gene, MRP2 
This gene is involved in drug efflux.
National Institutes of Health

Papers overview

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2014
2014
Methotrexate (MTX) is a key agent for the treatment of childhood acute lymphoblastic leukemia (ALL). Increased MTX plasma… (More)
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2011
2011
BACKGROUND Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux… (More)
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2010
2010
OBJECTIVE We used high-resolution peripheral vascular ultrasound imaging to assess endothelial function in hyperuricaemic… (More)
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2009
2009
OBJECTIVE We aimed to evaluate the association of non-response to antiepileptic pharmacotherapy with the frequency of variant… (More)
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2008
2008
Several studies have investigated the association between the ABCB1 polymorphism and drug-resistant epilepsy. However, the effect… (More)
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Highly Cited
1999
Highly Cited
1999
Human kidney proximal tubule epithelia express the ATP-dependent export pump for anionic conjugates encoded by the MRP2 (cMRP… (More)
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Review
1997
Review
1997
 The human Dubin-Johnson syndrome is an autosomal recessive liver disease characterized by a chronic conjugated… (More)
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Review
1997
Review
1997
The liver converts endogenous and xenobiotic lipophilic compounds into anionic conjugates with glutathione, glucuronate, or… (More)
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Highly Cited
1996
Highly Cited
1996
The Dubin-Johnson syndrome is characterized by an inherited defect in the secretion of amphiphilic anionic conjugates from… (More)
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1987
1987
Nuclear respiratory deficient mutants of Saccharomyces cerevisiae impaired in mitochondrial protein synthesis have been screened… (More)
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