Canalicular Multispecific Organic Anion Transporter 1

Known as: ATP-Binding Cassette Sub-Family C Member 2, Multidrug Resistance-Associated Protein 2, Canalicular Multidrug Resistance Protein 
Canalicular multispecific organic anion transporter 1 (1545 aa, ~174 kDa) is encoded by the human ABCC2 gene. This protein is involved in both anion… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Transgenic crops producing insecticidal toxins from Bacillus thuringiensis (Bt) are commercially successful in reducing pest… (More)
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Review
2010
Review
2010
ABCC2/Abcc2 (MRP2/Mrp2) is expressed at major physiological barriers, such as the canalicular membrane of liver cells, kidney… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Standard therapy for advanced ovarian cancer consists of a platinum agent in combination with a taxane, which has a 5… (More)
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Review
2006
Review
2006
A variety of drug transporters expressed in the body control the fate of drugs by affecting absorption, distribution, and… (More)
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Review
2004
Review
2004
The vectorial transport of bile salts from blood into bile is essential for the generation of bile flow, solubilization of… (More)
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Highly Cited
2004
Highly Cited
2004
This study aimed to characterize possible relationships between polymorphisms in the drug transporter genes organic anion… (More)
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Highly Cited
2002
Highly Cited
2002
Human organic anion transporting polypeptide 2 (OATP2/SLC21A6) and multidrug resistance-associated protein 2 (MRP2/ABCC2) play… (More)
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2001
2001
The ATP-binding cassette (ABC) proteins comprise a large superfamily of transmembrane transporters that utilize the energy of ATP… (More)
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Highly Cited
2000
Highly Cited
2000
We investigated the role of cMOAT/MRP2 (canalicular multispecific organic anion transporter/multidrug resistance-associated… (More)
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Review
1997
Review
1997
The liver converts endogenous and xenobiotic lipophilic compounds into anionic conjugates with glutathione, glucuronate, or… (More)
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